a16z Raises $15B, Projects Crypto Growth Through Markets and Infrastructure

In Brief

• a16z raises $15B to back AI, crypto, and innovation across multiple sectors.
• Prediction markets, cryptographic proofs, and staked media drive 2026 crypto growth.
• Fund aims to secure U.S. leadership and support entrepreneurs globally.

Andreessen Horowitz raised over $15 billion across multiple venture strategies in 2025. Funds include American Dynamism ($1.176B), Apps ($1.7B), Bio + Health ($700M), Infrastructure ($1.7B), Growth ($6.75B), and other strategies ($3B).

The raise accounted for more than 18% of all U.S. venture capital in 2025. a16z said these funds aim to support entrepreneurs, technological growth, and global competitiveness in AI and crypto.

The firm emphasized that giving people opportunities drives societal progress. Investments target human flourishing, with projects spanning AI, crypto, biology, health, defense, public safety, education, and entertainment.

Crypto’s Next Phase Focuses on Markets, Proofs, and Media

a16z crypto predicts 2026 will focus on markets, computing infrastructure, and media rather than new blockchains. Prediction markets like Polymarket and Kalshi are expected to expand and integrate AI for accuracy.

Cryptographic proofs will move beyond blockchains to enterprise systems. Zero-knowledge virtual machines reduce computation costs, enabling verifiable cloud computing for businesses and consumer devices.

The rise of staked media allows creators to align incentives with public claims. Tokenized assets, on-chain histories, and programmable lockups provide transparency and credibility amid AI-generated content.

a16z stressed that privacy will remain a critical competitive advantage for blockchain networks. Investors should track prediction markets, cryptographic proofs, and staked media to understand the next stage of crypto adoption.

The firm frames its crypto and tech investments as part of a broader mission to ensure American leadership in innovation. a16z aims to foster technological progress, support entrepreneurs, and secure strategic advantages in the global AI and crypto landscape.