Synthetix Founder Expects Other Perp DEXs to Follow Return to Ethereum Mainnet

• Synthetix’s migration back to Ethereum addresses past congestion issues, now resolved through scaling solutions.

• Layer-2 advancements and reduced gas fees make Ethereum mainnet viable for complex derivatives trading once again.

• Ethereum’s average gas fee is now 0.71 gwei, a 26-fold decrease from 18.85 gwei a year ago, according to Etherscan data.

Discover why Synthetix is returning to Ethereum in 2025 for superior perpetual DEX performance. Explore low fees, high liquidity, and scaling innovations driving this crypto revival—stay ahead in DeFi trading today.

What is Synthetix’s Return to Ethereum and Why Does It Matter?

Synthetix’s return to Ethereum involves relocating its perpetual decentralized exchange (perp DEX) operations from layer-2 networks back to Ethereum’s mainnet, leveraging the blockchain’s enhanced performance. This move, announced by founder Kain Warwick, capitalizes on years of infrastructure improvements that have alleviated historical bottlenecks like high gas fees and network congestion. As a result, Synthetix aims to deliver faster, more cost-effective trading experiences, potentially influencing other DeFi platforms to follow suit and reinforcing Ethereum’s position as the leading smart contract platform.

Previously, Synthetix had shifted to Ethereum layer-2 solutions such as Optimism in 2022, followed by expansions to Arbitrum and Base, in response to Ethereum’s scalability challenges. These migrations were common among DeFi projects seeking lower costs and higher throughput. However, with Ethereum’s ongoing upgrades, including the Dencun upgrade earlier in 2024 and subsequent optimizations, the mainnet now supports advanced financial primitives without the trade-offs of secondary layers.

Warwick emphasized in a recent interview that the timing is ideal: “By the time perp DEXs became a thing, the mainnet was too congested, but now we can run it back.” This sentiment underscores a broader trend in the ecosystem, where Ethereum’s core layer is regaining appeal for mission-critical applications. The platform’s total value locked (TVL) remains the highest among blockchains, exceeding $50 billion as of late 2025, according to DeFiLlama metrics, providing a fertile ground for liquidity aggregation.

Why Were High Gas Fees a Barrier for Perp DEXs on Ethereum?

High gas fees and network congestion historically rendered Ethereum mainnet unsuitable for perpetual DEXs, which require low-latency, high-volume transactions to maintain competitive markets. Warwick noted that “the cost per transaction and therefore the efficiency of the markets on the chain really degraded,” pushing platforms like Synthetix to layer-2 alternatives. For instance, during peak periods in 2021 and 2022, fees often surged above $50 per transaction, making it economically unviable for retail and institutional traders alike.

Today, Ethereum’s average gas fee has plummeted to approximately 0.71 gwei, nearly 26 times lower than the 18.85 gwei recorded on the same day a year prior, per Etherscan data. This reduction stems from a combination of proto-danksharding (EIP-4844) implementations, blob transactions, and decreased overall demand post-bear market. Layer-2 rollups have absorbed much of the load, but Warwick argues that layer-1 improvements now allow “critical infrastructure” to thrive directly on mainnet without intermediaries.

Expert analysis from Ethereum educator Anthony Sassano supports this view, stating that plans to elevate the gas limit to 180 million in 2026 represent a conservative target amid rapid development. Such enhancements could further boost throughput to over 100 transactions per second on layer-1, rivaling some layer-2 speeds while preserving Ethereum’s security model. For perp DEXs, this translates to tighter spreads, reduced slippage, and enhanced oracle integrations—key factors for derivatives trading reliability.

The decentralized derivatives space has evolved significantly since dYdX’s transition to StarkWare’s StarkEx layer-2 in 2021, highlighting the industry’s adaptive nature. Synthetix’s pivot back demonstrates confidence in Ethereum’s roadmap, including future upgrades like Prague-Electra, which aim to optimize execution layers for financial use cases.

Frequently Asked Questions

What prompted Synthetix to move away from Ethereum initially?

Synthetix migrated from Ethereum mainnet in 2022 due to prohibitive gas fees and congestion that hampered efficient perpetual trading. These issues degraded market efficiency and increased operational costs, leading many DeFi projects, including Synthetix, to adopt layer-2 networks like Optimism for better scalability and affordability.

How will Synthetix’s return impact liquidity in the DeFi ecosystem?

Synthetix’s return to Ethereum is expected to consolidate liquidity by tapping into the mainnet’s vast reserves of assets and margin, creating more efficient on-chain markets. This shift could attract higher trading volumes, benefiting users with deeper liquidity pools and lower costs, as Ethereum hosts the majority of crypto’s total liquidity.

Key Takeaways

• Ethereum’s Scalability Revival: Recent upgrades have slashed gas fees by over 25 times, making mainnet suitable for high-frequency trading like perpetual DEXs.
• Synthetix’s Strategic Move: By returning from layer-2s, Synthetix leverages Ethereum’s dominant liquidity and security, potentially setting a precedent for other platforms.
• Future-Proofing DeFi: Ongoing developments, including gas limit increases, position Ethereum as the go-to chain for critical financial infrastructure—monitor updates to optimize your trading strategies.

Conclusion

Synthetix’s return to Ethereum underscores the network’s transformation into a robust platform for perpetual DEXs and advanced DeFi applications, driven by lower fees, enhanced scaling, and unmatched liquidity. As founder Kain Warwick predicts, this could spark a wave of migrations back to mainnet, revitalizing Ethereum’s role in crypto finance. With 2025 marking a pivotal year for builder-focused innovations since the Merge, staying informed on these shifts will be essential for traders and developers aiming to capitalize on the next phase of blockchain evolution—explore Ethereum-based opportunities to secure your position in the growing DeFi landscape.