Every 20 seconds, somewhere in the world, a leg is lost to diabetes. For decades, that statistic felt inescapable. Today, physicians like Michael Lebow, MD are proving it doesn’t have to be.
The Hidden Crisis beneath the Skin
Diabetes quietly attacks the feet long before most patients notice. High blood sugar damages nerves (neuropathy) and hardens arteries (peripheral artery disease, or PAD). A small crack or callus that would heal in days on a healthy foot can become a deep, non-healing ulcer in someone with diabetes. Infection sets in quickly, tissue dies, and suddenly amputation becomes the “safest” option.
The numbers are sobering:
- Diabetic foot ulcers affect 19–25% of people with diabetes during their lifetime
- Up to 85% of amputations are preceded by an ulcer that never healed
- After a major amputation, five-year survival drops below 30% — worse than many cancers
Yet in clinics led by specialists like Dr. Michael Lebow, these outcomes are becoming the exception rather than the rule.
From Fatalism to Foot Salvation: A Brief History
In the pre-insulin era of the 1890s, diabetic gangrene was almost universally fatal. Surgeons amputated high and fast, hoping to outrun sepsis. The discovery of insulin in 1921 kept patients alive longer — but revealed foot complications as the new leading cause of hospitalization.
Real change began in the 1950s and 1960s:
- 1957 – First successful femoral-popliteal bypass grafts
- 1964 – Charles Dotter performs the world’s first angioplasty in a leg
- 1980s – Podiatry emerges as a distinct specialty focused on offloading and prevention
- 1990s – Multidisciplinary “toe and flow” clinics prove that combining vascular surgery with expert wound care dramatically lowers amputation rates
Michael Lebow, MD trained during this revolutionary period and saw firsthand how quickly the field was advancing. “When I started,” he recalls, “we were still telling patients, ‘If we can’t get blood down there, the leg is lost.’ Today, that sentence almost never leaves my mouth.”
The Three Pillars of Modern Limb Salvage
Pillar 1: Restoring Blood Flow with Endovascular Precision
More than half of all diabetic foot ulcers have critically reduced blood supply as a root cause. Without oxygen and nutrients, even the best wound dressing is useless.
Michael Lebow, MD specializes in minimally invasive endovascular revascularization — procedures performed through a needle hole rather than open surgery. Using live X-ray guidance, he threads ultra-thin wires and balloons into arteries as small as 1–2 millimeters in the foot itself.
Common techniques in his arsenal include:
- Drug-coated balloons that release medication to prevent re-narrowing
- Orbital and directional atherectomy devices that “sand” away rock-hard calcium
- Ultra-long stents designed specifically for below-knee arteries
- Pedal access — entering arteries through the top of the foot or even the heel when leg arteries are completely blocked
Published limb-salvage rates with these modern techniques now exceed 85–90% at one year, even in patients previously labeled “no-option.”
Pillar 2: Advanced Wound Healing That Goes Beyond Bandages
Once blood flow is restored, the wound itself must be coaxed into closing. This is where old-school thinking ends and science begins.
Dr. Michael Lebow’s wound-care protocol follows evidence-based international guidelines but is tailored to each patient:
- Weekly sharp debridement in the office to remove biofilm and stimulate growth factors
- Application of living skin substitutes (such as placental or bioengineered grafts) when healing stalls
- Negative-pressure wound therapy (wound VAC) to draw edges together and reduce swelling
- Total contact casting — the gold standard for offloading plantar ulcers, healing 70–90% within 6–12 weeks
“Endovascular work buys us time,” Dr. Lebow explains. “Expert wound care is what actually closes the ulcer and keeps it closed.”
Pillar 3: The Multidisciplinary Team — Where the Magic Happens
No single specialist can win this fight alone. Dr. Michael Lebow leads a weekly Limb Preservation Conference that brings together:
- Endocrinologists (tight glucose control)
- Podiatrists (custom orthotics and surgical offloading)
- Infectious disease physicians (targeted long-term antibiotics)
- Vascular nurses and wound-care certified staff
- Orthotists and pedorthists
- Social workers and behavioral health specialists
Studies of similar programs show amputation rates drop 45–85% compared with traditional care. Patients see every specialist in one visit, decisions are made collaboratively, and follow-up is relentless.
Real Patients, Real Results
Consider James R., a 58-year-old truck driver with a non-healing heel ulcer and no palpable pulses in either foot. Traditional surgeons recommended below-knee amputation. Instead, Dr. Michael Lebow performed a four-hour endovascular reconstruction of all three tibial arteries, followed by eight weeks of total contact casting and placental graft application. Today James is back on the road — both feet intact.
Or take Maria G., whose story opened this article. Three months after her combined endovascular and wound-care treatment under Dr. Lebow’s direction, she danced at her granddaughter’s quinceañera — something she never thought possible.
Looking Ahead: The Next Frontier
Dr. Michael Lebow is already incorporating promising innovations:
- Bioresorbable scaffolds that dissolve after keeping the artery open
- Artificial-intelligence algorithms that predict which ulcers are about to explode into major problems
- Home-based perfusion monitoring so patients can transmit foot oxygen levels to the team daily
But he is quick to emphasize that technology alone is never enough. “The most powerful tool we have,” Dr. Lebow says, “is still the simple act of listening to the patient, examining the foot thoroughly, and refusing to accept amputation as inevitable.”
A Message of Hope
For too long, diabetic foot disease has been treated as an unavoidable tragedy. Visionaries like Michael Lebow, MD are proving it is a treatable condition — when caught early and managed aggressively with the right combination of blood-flow restoration, advanced wound healing, and coordinated team care.
If you or someone you love has diabetes, inspect those feet daily. Seek help at the first sign of trouble. And remember: in 2025, losing a leg to diabetes is no longer fate. It’s a failure we can prevent — one limb, one team, one determined physician at a time.


