Best PPC Agencies for Enterprise Brands

Paid media has changed fast.  

Automation runs most bidding. AI shapes targeting. And enterprise campaigns now stretch across Google, Microsoft, YouTube, Meta, LinkedIn, Amazon, and a long list of retail media networks.  

That means bigger budgets and more data. Oh, and a lot more pressure to get everything working together. 

Enterprise brands need pay-per-click (PPC) partners who can handle that kind of scale. Teams that know how to plug into your data and guide automation instead of fighting it are among the elite.  

It’s no longer about flipping switches in an ad account. You need an agency partner who can manage the system.  

The best PPC agencies are the ones doing it right. Here’s a list of the ones we think fit the bill.   

 How We Evaluated These Agencies 

Enterprise PPC isn’t simple, so the evaluation behind this list couldn’t be, either. So, we looked at how the top PPC agencies handle that reality in the wild (not just on a pitch deck).  

Here’s a look at our methodology.  

 Scale 

The first thing we looked at was scale. Enterprise brands need partners who can run multi-market campaigns across layered account structures. If an agency struggles once spend gets serious, they didn’t make the cut. 

 Automation and AI 

We also dug into how each agency uses automation and AI. Platforms make the tools available, but the real difference comes from how a team guides bidding models and uses data to steer machine learning in the right direction. “Set it and forget it” agencies? Easy pass. 

 Full-Funnel Strategy 

Full-funnel strategy mattered, too. Enterprise campaigns stretch across brand and performance (and everything in between). That’s why we looked for teams that know how to connect those pieces and measure the impact across channels. 

 Data Maturity 

Strong enterprise PPC runs on data. Agencies with lifetime value (LTV) modeling, marketing mix modeling and multi-touch attribution (MMM/MTA) frameworks, custom dashboards, and clean customer relationship management (CRM) integrations scored higher. These are the teams that make decisions backed by real signals instead of guesswork.  

 Omnichannel 

We also evaluated how well each agency performs across search, social, programmatic, retail media, and video. Enterprise results rarely come from one channel anymore, so the strongest partners can move with you across platforms without losing efficiency. 

 Industry Expertise and Recognition 

Enterprise PPC comes with unique challenges, including compliance, long sales cycles, multi-region rollouts, and complex measurement. Agencies with experience in enterprise-heavy industries (like SaaS, finance, healthcare, retail, or B2B) ranked higher. We also noted awards and thought leadership, since they show who’s pushing the industry forward versus repeating the same playbook. 

 Transparency 

Finally, we factored in transparency. Clear reporting, honest communication, and real visibility into performance are non-negotiable when you’re managing seven-figure budgets. 

Methodology transparency: Everything in this ranking of the best PPC agencies comes from public case studies, platform certifications, verifiable performance data, and a direct review of each agency’s service capabilities. 

 Quick Comparison: Top PPC Agencies for Enterprise Brands 

 Detailed Rankings: Top PPC Agencies for Enterprise Brands 

Here’s where we break down what each agency does best. In the sections below, you’ll get a quick look at who they’re built for, where they excel, and what kind of investment to expect. 

 1. NP Digital 

NP Digital is built for enterprise brands that live and breathe performance. The paid media team runs campaigns across search, social, YouTube, retail media, and programmatic with one core focus: growth you can measure. Everything runs through a data lens, be it forecasting, audience strategy, creative testing, or budget allocation. 

NPD’s proprietary tech and automation keep large accounts manageable at scale. LTV modeling and full-funnel measurement help enterprise teams see the actual impact on revenue, not just clicks or impressions.  

With strong case studies across B2B, SaaS, e-commerce, and global brands, NP Digital is a fit for companies that expect paid media to pull its weight in the broader growth model. 

 Best For 

• Large enterprises needing scalable, omnichannel PPC  

• B2B, SaaS, and e-commerce brands focused on measurable growth  

 Key Strengths 

• Deep analytics and forecasting  

• Global scalability across search, social, retail media, and programmatic  

• AI-assisted optimization and automation 

• Structured testing frameworks and audience segmentation  

 Initial Investment 

• High 

 2. Tinuiti 

Tinuiti is one of the biggest independent performance agencies in the U.S., and it shows in the depth of its paid media offering. The agency is strong across paid search, paid social, Amazon, retail media, and streaming, which makes it a natural fit for enterprise B2C and e-commerce brands with complex channel mixes. 

Tinuiti’s Mobius tech suite is a big differentiator. It supports measurement and optimization in a way that gives brands a clear, unified view of performance. Combine that with deep partnerships across Google, Meta, and Amazon, and you get an agency that can move quickly while still aligning with long-term brand goals. 

 Best For 

• Large B2C and retail enterprises  

• Mid-market to Fortune 500 e-commerce brands  

• Retail brands investing heavily in Amazon and retail media  

 Key Strengths 

• Robust proprietary tech (Mobius) for activation and measurement  

• Strong retail media and marketplace expertise  

• Full-funnel paid media strategy, from awareness to conversion  

• Deep platform partnerships and certifications  

 Initial Investment 

• Medium–high (depending on scope) 

 3. Brainlabs 

Brainlabs leans into experimentation and automation more than most agencies. It’s built for brands that want to squeeze every bit of performance out of their media through structured testing and custom-built tools. If your organization loves spreadsheets and engineering-led solutions, Brainlabs will feel like home. 

It manages campaigns across Google, Microsoft, Meta, Amazon, and programmatic platforms, but the real story is how it uses custom bidding and modeling to drive results.  

Enterprise teams with complex accounts and a strong data culture tend to get a lot of value from Brainlabs’ approach. 

Best For 

• Global brands with complex account structures  

• Enterprises looking for custom automation and bidding systems  

 Key Strengths 

• Strong engineering culture and proprietary tools  

• Advanced experimentation and testing frameworks  

• Multi-channel management across major paid platforms  

 Initial Investment 

• High 

 4. Wpromote 

Wpromote positions itself as a “challenger” agency, and that mindset comes through in how it approaches enterprise PPC. The agency brings paid media and creative strategy together so campaigns feel cohesive from first touch to conversion. That puts it among the top PPC agencies for brands that want one partner to handle both performance and storytelling. 

Wpromote is particularly strong in B2C verticals like hospitality and finance. And it invests heavily in MMM and attribution, which helps larger organizations justify spend and more confidently plan future growth. 

 Best For 

• Large B2C brands in retail, hospitality, education, and finance  

• Enterprises that want tight alignment between creative and media  

 Key Strengths 

• “Challenger mindset” with a strategic and creative focus  

• Strong mix of paid search, paid social, and video  

• In-depth forecasting, MMM modeling, and attribution capabilities  

• Brand-meets-performance campaign mindset  

 Initial Investment 

• Medium–high 

 5. Merkle 

Merkle sits at the intersection of data and media, which is exactly where many enterprise brands need help. The agency is among the top PPC agencies for organizations with big CRM or customer data platform (CDP) investments that want to push that data into smarter PPC and cross-channel orchestration. 

With proprietary identity graphs and deep integrations into platforms like Adobe and Salesforce, Merkle can build audience strategies that go far beyond basic targeting. It’s particularly strong in regulated industries and large global enterprises. 

 Best For 

• Global enterprises with complex marketing technology (martech) stacks  

• Companies in regulated industries like finance, healthcare, and insurance  

 Key Strengths 

• Proprietary identity and audience modeling  

• PPC tied to customer journey orchestration and CRM data  

• Deep integration with Adobe, Salesforce, and enterprise martech  

 Initial Investment 

• High 

 6. Disruptive Advertising 

Disruptive Advertising is a good fit for brands that care as much about what happens after the click as they do about the click itself. The agency pairs strong PPC execution with conversion rate optimization (CRO) and landing page optimization. And that’s great for enterprises that want revenue gains (and not just nicer-looking dashboards). 

The Disruptive team runs serious programs on Google and Meta, backed by a creative studio that produces ad creative and video built to be tested. If you’re looking to scale budgets profitably and you know landing pages are a weak link, Disruptive is worth a look. 

 Best For 

• Enterprise e-commerce and high-velocity B2C brands  

• Companies that need a combined CRO and PPC partner  

 Key Strengths 

• Strong Google and Meta media management  

• In-house creative studio for ads and video  

• Heavy focus on landing page performance and CRO  

• Tight testing frameworks and transparent reporting  

Initial Investment 

• Medium 

 7. DEPT 

DEPT, which absorbed 3Q Digital, offers a highly technical, analytics-heavy approach to PPC. The agency is suited for B2B, SaaS, fintech, and other categories where LTV, pipeline, and long sales cycles matter more than last-click return on ad spend (ROAS). If your team lives in Salesforce or HubSpot all day, you’ll appreciate how DEPT thinks. 

The team at DEPT shines at blending paid search and paid social with machine learning. It also thrives at LTV modeling and custom automation. That makes the agency a strong partner for enterprise brands that need both scale and sophistication in how they measure and optimize paid programs. 

 Best For 

• B2B, SaaS, and fintech enterprises  

• Brands that want analytics-heavy, growth-focused PPC  

 Key Strengths 

• Industry-leading analytics and data science capabilities  

• Hybrid paid search and paid social strategies  

• LTV modeling and predictive forecasting  

• Custom scripts and automation for efficient scaling  

• Strong brand safety and compliance knowledge  

Initial Investment 

• Medium–high

 8. WebFX 

WebFX is a good match for enterprises that want strong performance and crystal-clear reporting. Its proprietary MarketingCloudFX platform pulls paid media, analytics, and attribution into one place, helping teams more easily figure out what’s working. 

The agency works across PPC, paid social, remarketing, and programmatic, but what stands out most is how accessible it makes the data. For organizations transitioning from small- and mid-sized business (SMB)-level PPC into more mature programs, WebFX offers structure without overwhelming teams. 

 Best For 

• Enterprises that prioritize transparent reporting and analytics  

• Large e-commerce and B2B brands  

• Organizations moving from SMB-level paid media to enterprise maturity  

 Key Strengths 

• MarketingCloudFX business intelligence (BI) platform for visibility and insight  

• Solid multi-channel PPC across search, social, remarketing, and programmatic  

• Strong attribution and reporting capabilities  

Initial Investment 

• Medium 

9. Seer Interactive 

Seer is built for data-obsessed brands. It taps into massive datasets, using SQL, BigQuery, and custom modeling to drive PPC strategy. If your team already has serious data infrastructure or wants an agency that can plug into it, Seer is a strong fit.  

It combines paid media with user intent and industry datasets, which helps uncover opportunities that basic platform reporting can’t. Seer is also known for its transparency and strong stance on data ethics, something enterprise brands increasingly care about. 

 Best For 

• Enterprise brands with large datasets and complex analytics stacks  

• Highly technical, data-driven organizations  

 Key Strengths 

• Massive internal data warehouse and analytics team  

• SQL and BigQuery-driven insight modeling  

• Blends paid media data with user intent and external signals  

• Known for transparency and innovation  

 Initial Investment 

• High 

 10. KlientBoost 

KlientBoost is a great option for enterprise teams that want aggressive testing and fast cycles. It brings a high-energy approach to experimentation across ads and funnels. That’s a refreshing approach if your current setup feels slow or stuck.  

The marketing agency combines paid search, paid social, and CRO under one roof, with a strong focus on clear cost-per-result improvements. If you have room to test and want a partner that leans into creative and landing page variation, KlientBoost is a solid contender.  

 Best For 

• Fast-moving enterprise teams  

• E-commerce and SaaS brands focused on testing and iteration  

 Key Strengths 

• Highly structured experimentation frameworks  

• Strong CRO and landing page integration  

• Paid search, paid social, and creative studio in one place  

 Initial Investment 

• Medium 

 11. HawkSEM 

HawkSEM leans hard into revenue. Its “Revenue-Driven Optimization” framework focuses on closed-won deals and long-term value instead of just lead volume. That resonates with enterprises in lead-gen heavy industries where not all leads are equal.  

It works well with SaaS, healthcare, senior living, education, and other sectors where quality and compliance matter. If you need an agency to help clean up lead quality and tie PPC performance back to CRM data, HawkSEM is a strong option. 

 Best For 

• Lead-generation-focused enterprises  

• SaaS, healthcare, senior living, and education brands  

• Organizations that need strict control over lead quality  

 Key Strengths 

• Focus on revenue and down-funnel impact  

• Strong support for complex B2B and lead-gen workflows  

• Google Premier Partner and Meta Partner  

 Initial Investment 

• Medium 

 12. JumpFly 

JumpFly is a pure-play PPC specialist with more than two decades of experience. It’s not trying to be everything. Rather, its focus is on getting search and Microsoft Ads right at a high standard. Enterprise teams that want reliability, technical quality, and clean accounts tend to appreciate that focus. 

The agency’s known for tight account hygiene, deep negative keyword work, and careful bid strategy. If you want a steady PPC partner to scale with over time, rather than a loud “growth hack” story, JumpFly is worth a serious look. 

 Best For 

• Enterprises wanting a dedicated PPC specialist  

• E-commerce, healthcare, and B2B brands seeking stable, long-term management  

 Key Strengths 

• Highly experienced, PPC-only agency  

• Strong Microsoft Ads expertise  

• Excellent account hygiene and technical execution  

• Consistent, reliable scaling over time  

Initial Investment 

• Medium 

 13. Single Grain 

Single Grain combines PPC with strategy, content, and creative, making it a good fit for brands that want a more holistic growth partner. It’s especially strong in B2B and SaaS spaces, as well as with info-driven businesses where demand gen and YouTube play big roles. 

It’s built a reputation around YouTube Ads and full-funnel campaigns, supported by thought leadership from founder Eric Siu. If you’re investing heavily in video and want PPC to plug into a larger growth system, Single Grain lines up well. 

 Best For 

• B2B and SaaS enterprises  

• Brands leaning into YouTube and video-heavy strategies  

 Key Strengths 

• Deep YouTube Ads experience  

• Strong strategic guidance and education-driven marketing  

• Multi-channel paid search and paid social  

• Testing-heavy approach with tight improvement loops  

Initial Investment 

• Medium–high 

14. Logical Position 

Logical Position is among the top PPC agency choices for enterprise e-commerce brands, especially those with large product catalogs. It’s good at the nuts and bolts of shopping feeds and scaling spend on Google and Microsoft with control.  

Beyond shopping ads, Logical offers remarketing, programmatic, and SEO, which can be useful for retailers that want one partner to handle a bigger slice of their digital presence. Its track record with high-stock keeping unit (SKU), retail-focused accounts is a key draw.  

 Best For 

• Large e-commerce enterprises  

• High-SKU retailers needing shopping and feed expertise  

 Key Strengths 

• Excellent feed optimization and merchant center management  

• Strong Google and Microsoft Ads execution  

• Programmatic and remarketing support  

• Integrated SEO and PPC services  

 Initial Investment 

• Medium 

15. Power Digital 

Power Digital blends paid media, creative, and influencer marketing with a strong analytics backbone. Its Nova platform gives brands a deeper view into performance and forecasting, which is helpful for enterprises running complex growth programs.  

It’s a good fit for direct-to-consumer (DTC) and lifestyle brands that want storytelling and performance to work together. With creative, paid social, and influencer all in-house, Power Digital can move quickly while still building campaigns that feel cohesive. 

Best For 

• DTC and lifestyle brands 

• B2C enterprises needing a tight creative and media combo  

• Multi-channel growth initiatives  

 Key Strengths 

• Nova analytics and forecasting platform  

• In-house paid social, content, and creative  

• Influencer integration with paid amplification  

• Strong storytelling-led performance campaigns  

 Initial Investment 

• Medium–high 

 Why Partner with an Enterprise PPC Agency? 

Enterprise PPC moves fast and gets complicated quickly. Larger brands deal with bigger datasets and more platforms, not to mention higher expectations.   

Not every team can keep up.   

The best PPC agencies bring structure to all of that. They help you turn raw data into models that improve forecasting and make budget allocation a lot less painful.  

They can also move with more testing velocity than most in-house teams can handle. That means more experiments and faster learning cycles.  

Enterprise agencies tend to be more comfortable with automation and AI, too. They know how to guide bidding systems and build predictive models that give you an edge.  

A good partner also helps with coordination across teams and markets. When you’re running search, social, retail media, and programmatic across countries, you need a system that keeps everything moving in the same direction. 

If your brand is growing across platforms or borders, or you just need more speed and sophistication in your paid media, partnering with a top PPC agency makes the whole operation run smoother. 

 How to Choose the Right Enterprise PPC Agency 

The right agency depends on what your team needs.  

Start with industry specialization. If you’re in SaaS, finance, healthcare, or e-commerce, look for an agency that already understands your world.  

Next, check their global capabilities. Enterprise campaigns stretch across regions, so you want a partner who can handle scale without losing accuracy. 

Data maturity is another big factor. Strong agencies bring real analytics. They don’t spend too much time dabbling in surface-level reporting or vanity metrics.  

Creative strategy matters, too. PPC is increasingly driven by messaging and testing loops, so make sure the agency has a content or creative engine that can keep pace.

And don’t overlook technology. Look for clean dashboards and clarity around how they use automation and machine learning. Don’t be afraid to ask for specifics. Dig into AI visibility reporting and examples of how they guide automated bidding. 

At the end of the day, choose a PPC agency that matches your scale while giving you clear visibility into what’s driving performance. 

 FAQs 

 What is a PPC agency? 

A PPC agency manages your paid media across platforms like Google, Microsoft, Meta, LinkedIn, YouTube, Amazon, and retail media networks. Its job is to help you reach the right audiences and convert them efficiently by running search, social, and programmatic campaigns. For enterprise brands, a PPC agency also handles things like audience modeling, forecasting, bid strategy, creative testing, and cross-channel measurement.

 How do you choose a PPC agency? 

Look for an agency with experience in your industry, strong analytics, clear reporting, and the ability to scale across channels and regions. Top PPC agencies will understand your goals and show exactly how they improve results.