ISRG vs JNJ Stock Comparison: Price, Growth & Valuation (2026)
Use MEXC Stock Compare for a detailed ISRG vs JNJ analysis. Compare ISRG and JNJ across price performance, growth, valuation, profitability and risk, based on market data and the latest reported financials.
ISRG vs JNJ Stock Comparison Summary
ISRG reported year-over-year revenue growth of 20.7%, compared with 8.1% for JNJ. Their P/E ratios are 45.8x and 30.3x, dividend yields are 0.00% and 1.98%, and 30-day volatility levels are 30.3% and 19.0%, respectively. These metrics highlight key differences in growth, valuation, dividend income and market risk. Overall JNJ leads across more of the selected comparison metrics.
Risk Disclaimer: MEXC Stock Compare provides information and comparisons on actual U.S.-listed stocks for reference only. Data may be delayed or inaccurate, does not constitute investment advice, and past performance does not guarantee future results.
ISRG vs JNJ Stock Return Comparison (1W)
Compare the cumulative total returns of Intuitive Surgical Inc. (ISRG) and Johnson & Johnson (JNJ) over the selected 1W period. Data as of 2026-10-01 12:00:00.
ISRG vs JNJ Key Equity Metrics Comparison Summary
Intuitive Surgical Inc. (ISRG) has a market capitalization of $143.28B and operates in the Health Care sector, with its main business classified under Health Care Equipment. Its latest quarterly revenue changed +20.7% year over year.
Johnson & Johnson (JNJ) has a market capitalization of $634.53B and operates in the Health Care sector, with its main business classified under Pharmaceuticals. Its latest quarterly revenue changed +8.1% year over year.
ISRG vs JNJ Key Stock Indicators
| Comparison Metric | ISRG | JNJ | Comparison results |
Stock Price & Returns Latest delayed stock price with 1-day, 1-month and year-to-date returns. | $405.561D: -1.4%1M: +7.9%1Y: -7.4% | $263.301D: -2.0%1M: -6.0%1Y: +41.5% | JNJWin |
Market Capitalization Total market value of the company's outstanding shares. | $143.28B | $634.53B | JNJWin |
Sector & Industry The company's market sector and primary industry classification. | Health Care / Health Care Equipment | Health Care / Pharmaceuticals | -- |
| Based on delayed market data, ISRG is trading at $405.56, compared with $263.30 for JNJ. Their market capitalizations are $143.28B and $634.53B, respectively. Both companies operate in the Health Care sector. | |||
| ISRG vs JNJ Growth & Profitability | |||
Revenue Growth (YoY) Year-over-year change in revenue. | +20.7% | +8.1% | ISRGWin |
EPS Growth (YoY) Year-over-year change in earnings per share. | +21.8% | -7.8% | ISRGWin |
ROIC Return generated from invested capital. | 18.7% | 18.7% | ISRGWin |
Gross Margin / Operating Margin Profitability before and after operating expenses. | 66.7% / 31.3% | 67.9% / 26.5% | JNJWin |
| On growth, ISRG posted revenue growth of +20.7% and TTM EPS growth of +21.8%. JNJ, by comparison, posted revenue growth of +8.1% and TTM EPS growth of -7.8%.On profitability, ISRG recorded a gross margin of 66.7%, an operating margin of 31.3%, and ROIC of 18.7%. For JNJ, the corresponding figures were 67.9%, 26.5%, and 18.7%.Overall, ISRG shows stronger overall growth and profitability. | |||
| ISRG vs JNJ Valuation & Balance Sheet | |||
Free Cash Flow Yield Free cash flow as a percentage of market capitalization. | 2.2% | 3.5% | JNJWin |
Net Debt / EBITDA Net debt relative to EBITDA; a negative value indicates net cash. | -0.8x | 0.8x | ISRGWin |
Dividend Yield / Payout Ratio Dividend returns relative to share price and the share of earnings paid as dividends. | 0.00% / 0.0% | 1.98% / 58.7% | JNJWin |
| JNJ offers a higher free cash flow yield, indicating a less demanding valuation. ISRG has the stronger balance sheet, while JNJ provides the higher dividend yield. Overall, the two stocks differ mainly in valuation, financial strength and dividend income. | |||
| ISRG vs JNJ Returns & Risk | |||
Total Return (Dividend-Adjusted) Cumulative return over 1, 5 and 10 years, including dividends. | 1Y: -7.4%5Y: +20.6%10Y: +408.7% | 1Y: +41.5%5Y: +64.1%10Y: +121.6% | ISRGWin |
30-Day Realized Volatility Annualized volatility based on the past 30 days of daily returns. | 30.3% | 19.0% | JNJWin |
Beta (5Y vs S&P 500) Sensitivity to market movements; above 1 indicates greater market volatility. | 1.25 | 0.16 | JNJWin |
| JNJ has delivered stronger long-term returns, but ISRG also shows higher recent volatility and market sensitivity. | |||
ISRG vs JNJ Valuation & Dividend Metrics
Review ISRG compared with JNJ across valuation, cash flow and dividend metrics, including P/E, forward P/E, free cash flow yield and dividend yield. These figures are provided for reference only and do not represent a fair-value estimate, price target or investment recommendation.
| Metric | ISRG | JNJ | Comparison results |
|---|---|---|---|
Market Cap | $143.28B | $634.53B | JNJWin |
P/E (TTM) | 45.8x | 30.3x | JNJWin |
P/S | 13.0x | 6.5x | JNJWin |
EV/EBITDA | 33.8x | 19.7x | JNJWin |
Dividend Yield | 0.00% | 1.98% | JNJWin |
ISRG vs JNJ Profitability Over Time
Compare ISRG and JNJ across gross margin and operating margin trends over time to understand how each company's profitability has changed. Based on reported financial data only; not a forecast or investment advice.
| TTM | 3Y Avg | 5Y Avg | 10Y Avg | |
|---|---|---|---|---|
| ISRG | 66.0% | 66.6% | 67.3% | 68.2% |
| JNJ | 67.9% | 68.6% | 69.1% | 68.1% |
Technical & Fundamental Stock Analysis
RSI (14, daily)
ISRG 61.60 • JNJ 40.85
Measures short-term price momentum and helps identify possible overbought or oversold conditions.
50/200-DMA Position
ISRG 50D Above / 200D Below • JNJ 50D Below / 200D Above
Shows whether the stock is trading above or below its medium- and long-term trend lines.
R&D % of Revenue
ISRG 12.8% • JNJ 15.5%
Shows how much of revenue is invested in research and development.
Share Count Trend (3Y)
ISRG Increased • JNJ Decreased
Shows whether the company's share count has increased or decreased over the past three years.
Company Profiles
Intuitive Surgical Inc.
Health Care Equipment
Intuitive develops, produces, and markets a robotic system for assisting minimally invasive surgery. It also provides the instrumentation, disposable accessories, and warranty services for the system. The company has placed more than 11,000 da Vinci systems in hospitals worldwide, with more than 6,600 installations in the US and a growing number in emerging markets.
Johnson & Johnson
Pharmaceuticals
Johnson & Johnson is the world's largest and most diverse healthcare firm. It has two divisions: innovative medicine and medtech. These now represent all of the company's sales following the divestment of the consumer business, Kenvue, in 2023. After restructurings in 2023-24, the drug division focuses on three main therapeutic areas: immunology, oncology, and neurology. Geographically, just over half of total revenue is generated in the United States.
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Everything You Need to Know About ISRG vs JNJ Stocks
What is MEXC Stock Compare?
MEXC Stock Compare is a side-by-side US stock comparison tool. It helps users compare two companies across stock price performance, market cap, valuation, growth, profitability, balance-sheet strength, dividends and risk. The results are provided for research purposes only and do not constitute investment advice.
Which metrics should I use to evaluate a company's growth?
Start with revenue growth to see how quickly the business is expanding, then review EPS growth to determine whether that growth is translating into higher earnings per share. Gross margin, operating margin and ROIC help assess the quality of that growth by showing profitability and capital efficiency. A company with fast revenue growth but declining margins may be expanding without improving its earnings quality.
How do ISRG and JNJ compare in growth and profitability?
In the latest reported period, ISRG recorded revenue growth of +20.7% and TTM EPS growth of +21.8%, compared with +8.1% and -7.8% for JNJ. ISRG leads on both growth and profitability. This comparison is based on reported financial metrics and does not predict future performance.
What is the difference between P/E (TTM) and Forward P/E?
P/E (TTM) compares the current share price with actual earnings reported over the past 12 months. Forward P/E uses estimated earnings for the next 12 months, so it reflects market expectations but depends on forecasts that may change. Both ratios should be considered alongside growth, profitability and industry peers.
How do the risk profiles of ISRG and JNJ compare?
ISRG has a 30-day realized volatility of 30.3% and a five-year Beta of 1.25, compared with 19.0% and 0.16 for JNJ. ISRG shows higher historical volatility and market sensitivity. These indicators describe historical price movements and market sensitivity, but they do not cover every source of investment risk.
What do dividend yield and payout ratio indicate?
Dividend yield shows the annual dividend relative to the current share price, while the payout ratio shows how much of a company's earnings is distributed as dividends. A higher yield may provide more income, but it can also rise because the share price has fallen. Dividend sustainability should therefore be considered together with earnings, cash flow and the payout ratio.
How should I compare a high-growth stock with a lower-valued stock?
A high-growth stock may trade at a higher valuation if investors expect its revenue and earnings to continue expanding. A lower-valued stock may offer a more conservative entry point, but the lower valuation could also reflect slower growth or higher business risk. Growth, valuation, profitability, cash flow and risk should therefore be considered together.
Which is the better stock, ISRG or JNJ?
There is no single answer for every investor. Growth-focused investors may place greater weight on revenue growth, EPS growth and ROIC, while income-focused investors may prioritize dividend yield and payout sustainability. Investors with lower risk tolerance may focus more on volatility, Beta and balance-sheet strength. MEXC Stock Compare presents the relevant metrics but does not provide a buy or sell recommendation.
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Disclaimer
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