Dow Jones
52,353.65
Change
-7.93-0.02%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are mixed today. The Dow Jones is -0.02%, the S&P 500 is +0.33%, and the Nasdaq Composite is +0.64%. Across individual stocks, 538 are advancing while 4,577 are declining, suggesting a mixed market tone.
S&P 500
7,701.88
Change
+25.11+0.33%
Nasdaq Composite
26,337.249
Change
+167.868+0.64%
24H Gainers
538
24H Losers
4,577
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 1 | Eloxx Pharmaceuticals, Inc.ELOX | $12.70 | -3.05% | 2.94K | $51.26M | $12.55 - $23.40 | 0.00% |
| 2 | Mega Fortune Company LimitedMGRT | $118.07 | -1.61% | 879 | $1.62B | $4.04 - $170.00 | 0.00% |
| 3 | Bank of New York Mellon CorporationBNY | $147.81 | +0.33% | 568.02K | $100.29B | $10.05 - $165.84 | 0.02% |
| 4 | TJGC Group LimitedTJGC | $31.64 | -3.18% | 68.09K | $319.51M | $1.46 - $36.76 | 0.00% |
| 5 | Nine Energy Service, Inc.NINE | $7.85 | -2.79% | 9.42K | $107.41M | $0.29 - $13.23 | 0.00% |
| 6 | AXT Inc.AXTI | $57.61 | +1.28% | 6.59M | $3.78B | $5.86 - $143.16 | 0.00% |
| 7 | Moderna, Inc.MRNA | $197.54 | -0.89% | 10.91M | $78.87B | $22.28 - $254.48 | 0.00% |
| 8 | Sandisk CorporationSNDK | $1,306.64 | +4.06% | 4.29M | $178.93B | $164.56 - $2,354.39 | 0.00% |
| 9 | BUUU Group LimitedBUUU | $5.46 | -23.47% | 1.13M | $7.73B | $0.57 - $7.31 | 0.00% |
| 10 | MMTec, Inc.MTC | $5.40 | -5.11% | 1.54K | $537.48M | $0.25 - $9.10 | 0.00% |
| 11 | Erasca, Inc.ERAS | $15.13 | +0.80% | 1.85M | $5.29B | $2.10 - $24.28 | 0.00% |
| 12 | Iovance Biotherapeutics, Inc.IOVA | $14.54 | +5.55% | 5.31M | $6.59B | $1.76 - $15.37 | 0.00% |
| 13 | SELLAS Life Sciences Group, Inc.SLS | $11.91 | +4.59% | 2.53M | $2.41B | $1.39 - $15.88 | 0.00% |
| 14 | Space Exploration Technologies Corp.SPCX | $150.25 | +2.35% | 58.27M | $2.00T | $21.32 - $225.64 | 0.00% |
| 15 | 10x Genomics, Inc.TXG | $78.81 | +7.91% | 919.76K | $9.47B | $12.34 - $102.81 | 0.00% |
| 16 | CareDx, Inc.CDNA | $71.47 | +3.42% | 350.99K | $3.70B | $14.22 - $72.71 | 0.00% |
| 17 | Kodiak Sciences Inc.KOD | $90.45 | +1.92% | 437.54K | $5.68B | $15.83 - $104.00 | 0.00% |
| 18 | Climb Bio, Inc.CLYM | $10.03 | +12.88% | 2.33M | $576.09M | $1.64 - $18.33 | 0.00% |
| 19 | Twist Bioscience CorporationTWST | $157.41 | +8.09% | 872.71K | $9.87B | $23.30 - $219.71 | 0.00% |
| 20 | MaxLinear, Inc.MXL | $73.17 | +9.70% | 2.01M | $6.66B | $12.77 - $128.30 | 0.00% |
| 21 | Lumentum Holdings Inc.LITE | $870.10 | +6.17% | 3.90M | $78.82B | $184.20 - $1,143.00 | 0.00% |
| 22 | Micron Technology, Inc.MU | $931.52 | +2.76% | 11.39M | $1.05T | $192.59 - $1,255.00 | 0.00% |
| 23 | Avita Medical, Inc.RCEL | $15.97 | +4.94% | 256.14K | $491.50M | $3.22 - $16.10 | 0.00% |
| 24 | Anterix Inc.ATEX | $83.01 | +3.83% | 77.14K | $1.63B | $17.58 - $113.00 | 0.00% |
| 25 | New Century Logistics (BVI) LimitedNCEW | $16.88 | +0.51% | 10 | $54.00M | $2.80 - $20.83 | 0.00% |
| 26 | WISeSat.Space Holdings Corp.SAIQ | $7.40 | +10.33% | 4.29M | $102.93M | $1.76 - $9.94 | 0.00% |
| 27 | Spyre Therapeutics, Inc.SYRE | $96.81 | +4.82% | 332.41K | $9.87B | $21.14 - $110.17 | 0.00% |
| 28 | PACS Group, Inc.PACS | $47.45 | -2.92% | 318.48K | $7.51B | $10.31 - $49.78 | 0.00% |
| 29 | agilon health, inc.AGL | $89.07 | -1.33% | 30.98K | $1.50B | $7.48 - $133.04 | 0.00% |
| 30 | EuroDry LtdEDRY | $45.30 | +1.16% | 26.31K | $129.85M | $12.08 - $73.07 | 0.00% |
| 31 | Vince Holding Corp.VNCE | $10.93 | -3.33% | 116.14K | $141.52M | $1.95 - $13.78 | 0.00% |
| 32 | Veradermics, IncorporatedMANE | $138.37 | +0.28% | 146.84K | $5.80B | $32.00 - $141.75 | 0.00% |
| 33 | Ampco-Pittsburgh Corp.AP | $8.16 | +6.40% | 31.57K | $168.57M | $1.75 - $12.81 | 0.00% |
| 34 | SAIHEAT LimitedSAIH | $27.55 | -6.26% | 13.74K | $32.93M | $5.90 - $33.00 | 0.00% |
| 35 | Agencia Comercial Spirits LtdAGCC | $14.80 | +0.75% | 4.81K | $646.08M | $4.23 - $25.73 | 0.00% |
| 36 | QTREX Quantum Ltd.QTEX | $1.34 | +5.04% | 4.82M | $75.27M | $0.28 - $3.85 | 0.00% |
| 37 | Oruka Therapeutics, Inc.ORKA | $95.02 | +5.01% | 644.93K | $6.29B | $25.23 - $115.52 | 0.00% |
| 38 | Alto Ingredients, Inc.ALTO | $3.62 | -1.09% | 469.80K | $280.41M | $0.99 - $6.11 | 0.00% |
| 39 | Fastly, Inc.FSLY | $27.17 | +5.84% | 1.89M | $4.33B | $7.87 - $34.82 | 0.00% |
| 40 | Butterfly Network, Inc.BFLY | $7.18 | +7.73% | 2.13M | $1.76B | $1.90 - $10.21 | 0.00% |
| 41 | Biodesix, Inc.BDSX | $21.64 | +0.89% | 101.97K | $228.28M | $5.26 - $31.97 | 0.00% |
| 42 | Rallybio CorporationRLYB | $16.07 | -2.39% | 28.52K | $85.36M | $3.67 - $17.57 | 0.00% |
| 43 | Alpha Tau Medical Ltd.DRTS | $13.36 | +2.99% | 122.71K | $1.21B | $3.43 - $15.79 | 0.00% |
| 44 | ImmunityBio, Inc.IBRX | $8.54 | +8.77% | 6.02M | $9.05B | $1.95 - $12.43 | 0.00% |
| 45 | Revolution Medicines, Inc.RVMD | $185.99 | +1.25% | 564.49K | $39.86B | $55.40 - $224.31 | 0.00% |
| 46 | Maase Inc.MAAS | $12.16 | -0.08% | 13.71K | $112.49M | $3.51 - $24.90 | 0.00% |
| 47 | Dell Technologies Inc.DELL | $503.94 | +7.75% | 4.13M | $158.96B | $110.22 - $595.51 | 0.01% |
| 48 | Entravision CommunicationEVC | $6.20 | +1.63% | 184.70K | $513.79M | $1.98 - $13.74 | 0.03% |
| 49 | Q32 Bio Inc.QTTB | $8.65 | +2.60% | 162.39K | $257.51M | $1.91 - $23.57 | 0.00% |
| 50 | OmniAb, Inc.OABI | $4.89 | +5.64% | 363.30K | $709.64M | $1.30 - $5.43 | 0.00% |
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Eloxx Pharmaceuticals, Inc. (ELOX) currently leads with a 52-week gain of 1,179,627.27% as of 2026-10-27 17:00 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
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Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.