Dow Jones
52,396.13
Change
+34.55+0.07%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are mixed today. The Dow Jones is +0.07%, the S&P 500 is +0.57%, and the Nasdaq Composite is +1.12%. Across individual stocks, 2,435 are advancing while 2,682 are declining, suggesting a mixed market tone.
S&P 500
7,720.15
Change
+43.38+0.57%
Nasdaq Composite
26,463.622
Change
+294.241+1.12%
24H Gainers
2,435
24H Losers
2,682
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 51 | RF Acquisition Corp IIRFAI | $32.86 | -10.69% | 6.33K | $115.43M | $8.94 - $73.00 | 0.00% |
| 52 | MBX Biosciences, Inc.MBX | $52.80 | +4.99% | 119.39K | $2.54B | $16.91 - $72.64 | 0.00% |
| 53 | Western Digital Corp.WDC | $382.12 | +7.34% | 5.81M | $143.04B | $121.85 - $799.87 | 0.00% |
| 54 | Pulse Biosciences, Inc.PLSE | $52.70 | +0.53% | 155.80K | $3.73B | $12.56 - $58.90 | 0.00% |
| 55 | Seagate Technology Holdings PLCSTX | $674.29 | +4.87% | 4.54M | $153.33B | $217.67 - $1,145.00 | 0.00% |
| 56 | Bandwidth Inc.BAND | $49.57 | +4.94% | 290.05K | $1.50B | $12.50 - $79.08 | 0.00% |
| 57 | Forum Energy Technologies, Inc.FET | $90.11 | +1.27% | 47.82K | $1.01B | $26.00 - $91.53 | 0.00% |
| 58 | Tango Therapeutics, Inc.TNGX | $22.55 | +2.48% | 1.48M | $3.80B | $7.12 - $34.39 | 0.00% |
| 59 | Fossil Group, Inc.FOSL | $6.56 | +2.18% | 209.13K | $387.95M | $1.70 - $7.39 | 0.00% |
| 60 | RINGCENTRAL, INC.RNG | $86.35 | +0.16% | 730.28K | $6.45B | $24.14 - $98.14 | 0.00% |
| 61 | Okeanis Eco Tankers Corp.ECO | $94.29 | -2.83% | 484.91K | $3.70B | $31.75 - $100.68 | 0.00% |
| 62 | Lindblad Expeditions Holdings Inc.LIND | $35.62 | +2.74% | 271.64K | $2.34B | $11.37 - $36.97 | 0.00% |
| 63 | Vera Bradley, Inc.VRA | $6.13 | +3.19% | 224.48K | $175.89M | $1.39 - $6.43 | 0.00% |
| 64 | Vestis CorporationVSTS | $15.04 | +0.27% | 585.03K | $1.99B | $4.83 - $16.90 | 0.00% |
| 65 | Illumina Inc.ILMN | $281.07 | +3.50% | 977.03K | $42.44B | $94.00 - $309.35 | 0.00% |
| 66 | Nuvectis Pharma, Inc.NVCT | $18.20 | +0.16% | 72.38K | $594.12M | $5.55 - $29.27 | 0.00% |
| 67 | Shattuck Labs, Inc.STTK | $5.72 | +3.61% | 206.61K | $574.08M | $1.72 - $8.33 | 0.00% |
| 68 | Syntec Optics Holdings, Inc.OPTX | $7.03 | +6.10% | 91.06K | $282.97M | $1.18 - $14.92 | 0.00% |
| 69 | Marvell Technology, Inc.MRVL | $242.68 | +3.79% | 8.43M | $212.81B | $70.69 - $329.88 | 0.00% |
| 70 | StablecoinX Inc.USDE | $10.10 | -4.82% | 507.42K | $251.11M | $1.33 - $18.11 | 0.00% |
| 71 | AN2 Therapeutics, Inc.ANTX | $3.67 | +0.69% | 124.84K | $138.30M | $1.00 - $7.19 | 0.00% |
| 72 | Eton Pharmaceutcials, Inc.ETON | $49.90 | -1.43% | 126.42K | $1.43B | $14.27 - $66.37 | 0.00% |
| 73 | Andersen Group Inc.ANDG | $63.20 | -1.42% | 68.26K | $1.18B | $18.12 - $65.94 | 0.00% |
| 74 | DigitalOcean Holdings, Inc.DOCN | $107.66 | +7.94% | 1.54M | $11.24B | $37.84 - $187.50 | 0.00% |
| 75 | Aura Minerals Inc.AUGO | $80.98 | +5.41% | 304.04K | $6.79B | $29.11 - $110.32 | 0.00% |
| 76 | Globus Maritime LimitedGLBS | $2.99 | +0.37% | 48.11K | $64.55M | $1.04 - $4.06 | 0.00% |
| 77 | Pyxis Tankers Inc.PXS | $7.21 | -4.50% | 88.90K | $73.79M | $2.56 - $8.34 | 0.00% |
| 78 | Penguin Solutions, Inc.PENG | $59.32 | +7.85% | 1.30M | $3.57B | $16.04 - $89.86 | 0.00% |
| 79 | LifeStance Health Group, Inc.LFST | $13.07 | -0.34% | 1.01M | $5.00B | $4.77 - $13.56 | 0.00% |
| 80 | Hyperliquid Strategies Inc.PURR | $9.93 | +10.58% | 7.06M | $1.74B | $3.01 - $14.76 | 0.00% |
| 81 | Iridium Communications Inc.IRDM | $45.69 | +3.07% | 251.47K | $4.85B | $15.64 - $57.18 | 0.01% |
| 82 | NGL ENERGY PARTNERS LPNGL | $16.12 | +1.64% | 15.72K | $2.01B | $6.26 - $19.06 | 0.05% |
| 83 | TOP Financial Group LimitedTOP | $15.33 | +0.79% | 119.53K | $1.87B | $3.06 - $17.42 | 0.00% |
| 84 | Relay Therapeutics, Inc.RLAY | $18.65 | +2.81% | 1.01M | $4.09B | $5.95 - $21.27 | 0.00% |
| 85 | Ethos Technologies Inc.LIFE | $42.44 | +0.71% | 595.08K | $2.80B | $9.45 - $44.99 | 0.00% |
| 86 | Okta, Inc.OKTA | $226.58 | +2.99% | 1.33M | $37.87B | $62.66 - $235.00 | 0.00% |
| 87 | Aehr Test SystemsAEHR | $63.28 | +12.55% | 1.61M | $2.07B | $18.70 - $147.40 | 0.00% |
| 88 | Hewlett Packard Enterprise CompanyHPE | $60.84 | +3.56% | 6.55M | $80.76B | $19.84 - $73.56 | 0.01% |
| 89 | FIGS, Inc.FIGS | $20.50 | -1.34% | 1.16M | $3.24B | $7.21 - $20.89 | 0.00% |
| 90 | Guardant Health, Inc.GH | $177.70 | +2.02% | 655.64K | $23.85B | $68.02 - $191.05 | 0.00% |
| 91 | Paysign, Inc.PAYS | $14.60 | +3.26% | 350.42K | $824.35M | $3.08 - $16.15 | 0.00% |
| 92 | Able View Global Inc.ABLV | $2.36 | +1.98% | 84.26K | $57.84M | $0.54 - $2.86 | 0.00% |
| 93 | Tilly's Inc.TLYS | $4.20 | -0.24% | 74.50K | $97.69M | $1.14 - $6.25 | 0.00% |
| 94 | Edgewise Therapeutics, Inc.EWTX | $39.53 | +1.28% | 279.76K | $4.29B | $15.23 - $48.51 | 0.00% |
| 95 | Calumet, Inc.CLMT | $49.52 | -4.64% | 624.97K | $4.35B | $17.85 - $59.87 | 0.00% |
| 96 | First Tracks Biotherapeutics, Inc.TRAX | $45.70 | +5.24% | 328.38K | $1.57B | $14.72 - $49.91 | 0.00% |
| 97 | FormFactor Inc.FORM | $106.80 | +5.85% | 611.48K | $8.33B | $41.84 - $160.27 | 0.00% |
| 98 | Hongli Group Inc.HLP | $3.56 | +1.00% | 190.89K | $266.07M | $0.34 - $3.63 | 0.00% |
| 99 | Glaukos CorporationGKOS | $183.54 | +3.12% | 776.82K | $10.83B | $73.16 - $191.62 | 0.00% |
| 100 | Maravai LifeSciences Holdings, Inc.MRVI | $8.10 | +7.39% | 972.99K | $1.21B | $2.54 - $9.42 | 0.00% |
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
RF Acquisition Corp II (RFAI) currently leads with a 52-week gain of 207.13% as of 2026-10-27 17:50 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
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Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.