52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview

U.S. stocks are broadly higher today, with the Dow Jones up ⁦0.03%⁩, the S&P 500 up ⁦0.60%⁩, and the Nasdaq Composite up ⁦1.18%⁩. Market breadth is also positive, with 2,687 stocks advancing versus 2,431 declining, indicating a broadly bullish bias.

Dow Jones

52,377.57

Change

+15.99+0.03%

S&P 500

7,722.6

Change

+45.83+0.60%

Nasdaq Composite

26,477.811

Change

+308.43+1.18%

24H Gainers

2,687

24H Losers

2,431

52 Week Gainers

Large Cap Small Cap 52 Week Gainers 52 Week Losers Semiconductor Software Biotech Bank

#	Stock					52 Week Range
4101	Neostellar Capital Corp.NSLR	$5.83	+1.57%	239.75K	$154.47M	$5.72 - $12.54	0.00%
4102	The Simply Good Foods CompanySMPL	$9.74	-3.47%	3.88M	$861.34M	$9.38 - $22.00	0.00%
4103	GeneDx Holdings Corp.WGS	$62.61	+2.15%	645.79K	$1.87B	$32.21 - $170.87	0.00%
4104	Strategy Inc.MSTR	$141.46	+0.22%	8.63M	$56.91B	$81.81 - $299.80	0.00%
4105	PepGen Inc.PEPG	$2.60	+4.22%	1.27M	$179.73M	$1.31 - $7.80	0.00%
4106	American Superconductor Corp.AMSC	$27.62	+8.76%	662.89K	$1.34B	$24.08 - $64.72	0.00%
4107	5E Advanced Materials, Inc.FEAM	$2.50	+5.04%	364.45K	$103.91M	$0.90 - $6.03	0.00%
4108	SiNtx Technologies, Inc.SINT	$1.73	+13.46%	33.41K	$11.53M	$1.40 - $4.46	0.00%
4109	Springview Holdings LtdSPHL	$2.46	+2.29%	41.01K	$5.58M	$1.92 - $25.11	0.00%
4110	Beamr Imaging Ltd.BMR	$1.33	+2.28%	23.90K	$20.73M	$1.06 - $2.88	0.00%
4111	Plug Power Inc.PLUG	$1.41	+2.55%	42.09M	$1.96B	$1.34 - $4.33	0.00%
4112	Kyntra Bio, Inc.KYNB	$4.51	+0.45%	6.09K	$18.26M	$4.34 - $9.70	0.00%
4113	Ultragenyx Pharmaceutical Inc.RARE	$16.76	+4.23%	3.40M	$1.65B	$12.73 - $39.89	0.00%
4114	Alnylam Pharmaceuticals, Inc.ALNY	$226.72	-0.41%	1.38M	$30.34B	$197.81 - $485.36	0.00%
4115	ProKidney Corp.PROK	$1.52	+11.76%	1.19M	$318.61M	$1.30 - $3.48	0.00%
4116	Annovis Bio, Inc.ANVS	$1.02	+4.49%	892.95K	$43.45M	$0.93 - $5.50	0.00%
4117	ReposiTrak, Inc.TRAK	$7.21	+0.14%	111.79K	$131.21M	$6.94 - $15.80	0.01%
4118	Wrap Technologies, Inc.WRAP	$1.25	+8.70%	564.71K	$77.81M	$1.04 - $3.23	0.00%
4119	Sana Biotechnology, Inc.SANA	$2.48	+5.08%	2.13M	$740.92M	$2.22 - $5.70	0.00%
4120	Cerenome, Inc.CNSY	$1.66	+6.69%	50.52K	$12.59M	$1.49 - $4.16	0.00%
4121	Finance of America Companies Inc.FOA	$10.72	-2.45%	82.89K	$98.78M	$10.63 - $29.79	0.02%
4122	Pliant Therapeutics, Inc.PLRX	$0.85	-1.93%	340.90K	$52.45M	$0.83 - $1.95	0.00%
4123	Quhuo LimitedQH	$3.03	+1.13%	7.79K	$7.95M	$0.07 - $12.81	0.00%
4124	NioCorp Developments LtdNB	$3.42	+18.28%	3.77M	$498.05M	$2.81 - $8.18	0.00%
4125	Foxx Development Holdings Inc.FOXX	$2.00	-1.94%	13.50K	$14.16M	$1.71 - $7.90	0.00%
4126	HomesToLife LtdHTLM	$1.52	-1.62%	2.15K	$136.32M	$1.48 - $4.19	0.00%
4127	Clene Inc.CLNN	$3.98	+3.65%	30.25K	$51.70M	$3.02 - $13.50	0.00%
4128	Cineverse Corp.CNVS	$1.45	-1.35%	127.81K	$34.35M	$1.41 - $3.44	0.00%
4129	Standard BioTools Inc.LAB	$0.62	+3.83%	993.34K	$243.54M	$0.59 - $1.72	0.00%
4130	ProQR Therapeutics N.V.PRQR	$1.33	+7.66%	1.44M	$140.66M	$1.21 - $3.00	0.00%
4131	Versus Systems Inc.VS	$0.96	-1.53%	5.18K	$6.00M	$0.75 - $2.10	0.00%
4132	Passage Bio, Inc.PASG	$3.35	+1.36%	3.68K	$10.80M	$3.29 - $20.00	0.00%
4133	Tiziana Life Sciences LtdTLSA	$0.88	-0.77%	184.67K	$106.05M	$0.76 - $2.10	0.00%
4134	PAR Technology Corp.PAR	$16.87	-1.92%	700.68K	$697.83M	$11.59 - $40.54	0.00%
4135	Alzamend Neuro, Inc.ALZN	$1.14	-2.56%	8.59K	$5.50M	$0.84 - $2.68	0.00%
4136	Tron Inc.TRON	$1.41	+12.45%	981.64K	$666.51M	$1.05 - $3.08	0.00%
4137	Embecta Corp.EMBC	$6.54	-3.82%	1.12M	$370.72M	$2.77 - $14.91	0.07%
4138	Roze AI Inc.RZAI	$10.16	-4.46%	137.70K	$607.63M	$9.03 - $35.55	0.00%
4139	Destination XL Group, Inc.DXLG	$0.48	-0.46%	39.48K	$26.78M	$0.36 - $1.58	0.00%
4140	AecomACM	$61.54	+1.33%	500.02K	$7.92B	$56.39 - $135.52	0.02%
4141	Oracle Corp.ORCL	$130.55	+4.36%	22.61M	$394.76B	$114.50 - $287.00	0.02%
4142	Live Ventures Inc.LIVE	$7.53	+0.33%	523	$23.13M	$7.00 - $22.70	0.00%
4143	Forge Nano Holdings Inc.NANO	$4.67	-6.60%	277.54K	$775.45M	$4.07 - $11.96	0.00%
4144	Integrated Media Technology LimitedIMTE	$0.45	+1.18%	19.50K	$1.56M	$0.40 - $1.34	0.00%
4145	Duolingo, Inc.DUOL	$141.48	+2.03%	568.08K	$5.71B	$87.89 - $318.84	0.00%
4146	Waldencast plcWALD	$0.89	-2.00%	253.11K	$106.88M	$0.72 - $3.22	0.00%
4147	Yunhong Green CTI LtdYHGJ	$2.63	+3.46%	36.28K	$6.86M	$2.38 - $5.78	0.00%
4148	QuidelOrtho CorporationQDEL	$13.58	-1.38%	1.56M	$931.25M	$9.92 - $35.58	0.00%
4149	Airship AI Holdings, Inc.AISP	$2.29	+5.79%	318.26K	$78.69M	$1.69 - $5.23	0.00%
4150	Builders FirstSource, Inc.BLDR	$56.72	+0.87%	1.51M	$6.10B	$49.66 - $131.50	0.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?

These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.

How is the 52-week gain calculated?

It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.

Which stock has gained the most over 52 weeks?

Neostellar Capital Corp. (NSLR) currently leads with a 52-week gain of 52.01% as of 2026-10-28 05:08 UTC.

Why use a 52-week stock performance ranking?

It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.

Does strong 52-week performance guarantee future gains?

No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.

How is this different from the daily Top Gainers list?

The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.