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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly higher today, with the Dow Jones up ⁦0.03%⁩, the S&P 500 up ⁦0.60%⁩, and the Nasdaq Composite up ⁦1.18%⁩. Market breadth is also positive, with 2,687 stocks advancing versus 2,431 declining, indicating a broadly bullish bias.

Dow Jones
52,377.57
Change
+15.99+0.03%
S&P 500
7,722.6
Change
+45.83+0.60%
Nasdaq Composite
26,477.811
Change
+308.43+1.18%
24H Gainers
2,687
24H Losers
2,431

52 Week Gainers

#Stock52 Week Range
4351Proficient Auto Logistics, Inc.PAL$2.46-4.12%410.51K$68.87M$2.44 - $10.970.00%
4352Skillsoft Corp.SKIL$5.30-0.95%49.08K$48.23M$3.43 - $16.910.00%
4353Citius Oncology, Inc.CTOR$0.63+3.86%119.18K$58.49M$0.49 - $1.930.00%
4354Optimum Communications, Inc.OPTU$0.65-9.48%2.42M$178.26M$0.48 - $2.140.00%
4355ADC Therapeutics SAADCT$1.56+4.30%768.01K$199.80M$0.78 - $4.980.00%
4356Namib MineralsNAMM$0.75-9.60%609.82K$46.80M$0.72 - $7.420.00%
4357Voyager Therapeutics, Inc.VYGR$1.75-0.85%658.66K$107.52M$1.71 - $5.480.00%
4358CytoMed Therapeutics LimitedGDTC$0.88-3.30%6.59K$10.39M$0.68 - $3.100.00%
4359Rectitude Holdings LtdRECT$1.25-5.47%5.57K$19.24M$0.96 - $4.450.00%
4360Solarmax Technology Inc.SMXT$4.28+0.73%3.07K$20.30M$1.82 - $15.240.00%
4361GSI TechnologyGSIT$4.36+9.62%165.20K$167.57M$3.76 - $13.300.00%
4362Zenta Group Company LimitedZTG$0.67-2.01%75.68K$16.91M$0.55 - $12.250.00%
4363Datasea Intelligent Technology LtdDTSS$0.70+2.35%47.33K$10.37M$0.52 - $2.290.00%
4364PharmaCyte Biotech, Inc.PMCB$0.36+2.73%48.28K$3.83M$0.33 - $1.510.09%
4365Whirlpool Corp.WHR$26.68+1.12%8.81M$1.74B$24.00 - $94.820.10%
4366NeOnc Technologies Holdings, Inc.NTHI$2.98+4.26%44.08K$78.03M$2.50 - $12.000.00%
4367Gloo Holdings, Inc.GLOO$2.92+0.17%166.53K$270.93M$2.85 - $9.980.00%
4368Caring Brands, Inc.CABR$1.10-5.52%18.24K$10.89M$0.71 - $4.390.00%
4369MARA Holdings, Inc.MARA$7.01+3.07%27.02M$2.71B$6.62 - $20.470.00%
4370YD Bio LimitedYDES$6.13+15.69%36.56K$350.67M$1.70 - $17.990.00%
4371Oculis Holding AGOCS$7.72-2.83%100.84K$447.93M$7.11 - $34.480.00%
4372Fusion Fuel Green PLCHTOO$1.75-0.29%16.52K$13.12M$1.65 - $5.080.00%
4373Inovio Pharmaceuticals, Inc.INO$0.89+2.77%2.37M$92.02M$0.56 - $2.720.00%
4374Lithium Americas Corp.LAC$2.15+5.94%5.46M$809.38M$1.98 - $6.960.00%
4375Hyperion DeFi, Inc.HYPD$2.97+4.21%80.46K$46.15M$2.34 - $9.130.02%
4376Tao Synergies Inc.TAOX$3.15-1.25%87.84K$24.72M$3.06 - $9.430.02%
4377Nano Labs LtdNA$1.70+5.94%44.14K$34.98M$1.58 - $5.160.00%
4378Gix Internet Ltd.GIXI$4.25+3.86%31.34K$10.54M$3.56 - $15.500.00%
4379SkinHealth Systems Inc.SKIN$10.31-2.00%36.34K$70.88M$9.89 - $34.800.00%
4380Milestone Pharmaceuticals Inc.MIST$0.67+5.17%572.06K$83.91M$0.63 - $3.060.00%
4381Giftify, Inc.GIFT$0.41-14.97%204.11K$14.63M$0.38 - $1.290.00%
4382Aware Inc.AWRE$0.88+5.33%49.32K$19.22M$0.83 - $2.570.00%
4383AIxCrypto Holdings, Inc.AIXC$1.01-39.46%1.91M$21.32M$0.59 - $3.270.00%
4384Fiverr International Ltd.FVRR$8.12-2.23%415.04K$291.74M$8.11 - $23.850.00%
4385ECARX Holdings Inc.ECX$0.82+3.21%368.24K$255.24M$0.79 - $2.700.00%
4386Nerdy Inc.NRDY$5.69-1.19%1.76K$52.19M$5.48 - $22.350.00%
4387Papa John's International Inc.PZZA$17.93-2.08%767.90K$590.45M$17.70 - $55.050.10%
4388Lucid Diagnostics Inc.LUCD$0.44-10.96%7.06M$89.02M$0.30 - $1.630.00%
4389Solid Power, Inc.SLDP$2.02+2.01%1.85M$462.07M$1.91 - $8.860.00%
4390Claros Mortgage Trust, Inc.CMTG$1.22+0.41%542.44K$171.56M$1.09 - $3.620.00%
4391LifeMD, Inc.LFMD$2.13+1.92%257.63K$102.43M$2.06 - $6.420.03%
4392uniQure N.V.QURE$23.50+8.01%656.27K$1.63B$8.73 - $71.500.00%
4393C1 Fund Inc.CFND$2.66+1.55%2.35K$17.01M$2.04 - $7.900.00%
4394Rani Therapeutics Holdings, Inc.RANI$0.61-0.53%248.79K$70.87M$0.57 - $2.630.00%
4395Dyadic International, Inc.DYAI$0.41-1.41%64.22K$16.31M$0.34 - $1.600.00%
4396Bullfrog AI Holdings, Inc.BFRG$0.48-4.12%92.52K$8.84M$0.43 - $1.960.00%
4397Sound Point Meridian Capital, Inc.SPMC$5.70+1.97%10.15K$116.83M$5.50 - $16.750.00%
4398D-Wave Quantum Inc.QBTS$11.97+4.03%7.08M$4.42B$11.26 - $37.620.00%
4399ParaZero Technologies Ltd.PRZO$0.50+3.31%170.41K$13.02M$0.38 - $1.590.00%
4400Blend Labs, Inc.BLND$1.21+3.88%1.03M$281.07M$0.88 - $3.620.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Proficient Auto Logistics, Inc. (PAL) currently leads with a 52-week gain of 63.41% as of 2026-10-28 03:54 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.