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52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.10%⁩, the S&P 500 is ⁦+0.66%⁩, and the Nasdaq Composite is ⁦+1.29%⁩. Across individual stocks, 2,544 are advancing while 2,574 are declining, suggesting a mixed market tone.

Dow Jones
52,415.58
Change
+54.0+0.10%
S&P 500
7,727.65
Change
+50.88+0.66%
Nasdaq Composite
26,507.667
Change
+338.286+1.29%
24H Gainers
2,544
24H Losers
2,574

52 Week Losers

#Stock52 Week Range
5151CareDx, Inc.CDNA$70.95+2.63%663.50K$3.67B$14.22 - $72.710.00%
515210x Genomics, Inc.TXG$78.47+7.72%1.35M$9.43B$12.34 - $102.810.00%
5153Space Exploration Technologies Corp.SPCX$149.52+1.96%76.90M$2.00T$21.32 - $225.640.00%
5154SELLAS Life Sciences Group, Inc.SLS$12.08+6.88%5.02M$2.44B$1.39 - $15.880.00%
5155Erasca, Inc.ERAS$15.05+0.90%2.81M$5.27B$2.10 - $24.280.00%
5156Iovance Biotherapeutics, Inc.IOVA$14.59+6.02%6.70M$6.61B$1.76 - $15.370.00%
5157MMTec, Inc.MTC$5.57-2.16%6.10K$554.21M$0.25 - $9.100.00%
5158BUUU Group LimitedBUUU$5.61-10.68%1.68M$7.73B$0.57 - $7.310.00%
5159Sandisk CorporationSNDK$1,300.70+3.62%5.63M$178.93B$164.56 - $2,354.390.00%
5160Moderna, Inc.MRNA$206.10+3.78%14.82M$82.28B$22.28 - $254.480.00%
5161AXT Inc.AXTI$57.72+2.56%7.67M$3.78B$5.86 - $143.160.00%
5162Nine Energy Service, Inc.NINE$7.84-2.27%10.48K$107.41M$0.29 - $13.230.00%
5163TJGC Group LimitedTJGC$31.64-3.18%68.09K$319.51M$1.46 - $36.760.00%
5164Bank of New York Mellon CorporationBNY$148.09+0.67%927.31K$100.48B$10.05 - $165.840.02%
5165Mega Fortune Company LimitedMGRT$117.00-2.50%3.01K$1.61B$4.04 - $170.000.00%
5166Eloxx Pharmaceuticals, Inc.ELOX$12.91-1.52%4.76K$52.11M$12.55 - $23.400.00%

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Position typesBuy and holdBuy and holdLong, short, leveraged
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Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
CareDx, Inc. (CDNA) currently shows a 52-week decline of 388.96% as of 2026-10-27 19:29 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.