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52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are broadly higher today, with the Dow Jones up ⁦0.11%⁩, the S&P 500 up ⁦0.69%⁩, and the Nasdaq Composite up ⁦1.30%⁩. Market breadth is also positive, with 2,572 stocks advancing versus 2,546 declining, indicating a broadly bullish bias.

Dow Jones
52,419.3
Change
+57.72+0.11%
S&P 500
7,729.54
Change
+52.77+0.69%
Nasdaq Composite
26,510.589
Change
+341.208+1.30%
24H Gainers
2,572
24H Losers
2,546

52 Week Losers

#Stock52 Week Range
401Psyence Biomedical LtdPBM$3.04-17.21%243.26K$11.58M$1.92 - $21.250.00%
402Antalpha Platform Holding CompanyANTA$1.70+0.06%6.79K$47.07M$1.51 - $12.440.00%
403Newegg Commerce, Inc.NEGG$9.95+4.65%15.80K$208.69M$9.29 - $96.290.00%
404Moolec Science SAMLEC$1.54-1.28%26.00K$1.12M$1.34 - $23.220.00%
405Gemini Space Station, Inc.GEMI$3.08+7.32%1.69M$396.74M$2.81 - $20.930.00%
406The Metals Royalty Company Inc.TMCR$2.12-0.48%74.81K$142.92M$1.98 - $21.380.00%
407IQSTEL INC.IQST$0.89+3.37%140.75K$9.76M$0.83 - $6.280.00%
408OIO GroupOIO$1.77-1.62%104.06K$616.00M$1.36 - $11.550.00%
409Anavex Life SciencesAVXL$1.30+1.56%1.11M$120.97M$1.14 - $8.790.00%
410FMC CorporationFMC$4.71+2.16%7.30M$590.44M$4.56 - $30.950.23%
411Hang Feng Technology Innovation Co., Ltd.FOFO$1.99+4.19%3.06K$15.82M$1.70 - $14.930.00%
412Nixxy, Inc.NIXX$0.24-7.67%256.30K$6.94M$0.17 - $1.750.00%
413BioHarvest Sciences Inc.BHST$1.71-0.60%12.83K$28.10M$1.37 - $12.200.00%
414CISO Global, Inc.CISO$0.18-2.31%125.49K$8.30M$0.16 - $1.290.00%
415Amesite Inc.AMST$0.59-6.62%32.96K$3.84M$0.56 - $3.900.00%
416Foremost Clean Energy LtdFMST$0.61+13.27%400.26K$9.02M$0.42 - $3.970.00%
417PAVmed Inc.PAVM$2.13-6.19%8.51K$17.02M$1.84 - $28.440.00%
418Lantern Pharma Inc.LTRN$0.65+4.22%68.56K$9.65M$0.59 - $4.340.00%
419Ucommune International LtdUK$1.72-4.72%6.94K$1.14M$1.60 - $10.700.00%
420QumulusAI, Inc.QMLS$3.44+10.19%191.40K$107.07M$3.10 - $38.000.00%
421Acurx Pharmaceuticals, Inc.ACXP$1.06-1.85%55.78K$5.89M$1.02 - $7.540.00%
422Tantech Holdings LtdTANH$12.59+3.88%27.57K$11.82M$8.01 - $81.500.00%
423Ping An Biomedical Co., LtdPASW$4.81+6.92%50.10K$14.89M$3.07 - $30.800.00%
424Anbio BiotechnologyNNNN$3.89+1.35%21.27K$167.23M$3.09 - $44.730.00%
425Shuttle Pharmaceuticals Holdings, Inc.SHPH$5.21+3.33%10.20K$24.84M$2.58 - $44.400.00%
426SANUWAVE Health, Inc.SNWV$5.07+0.59%20.86K$43.58M$3.92 - $36.200.00%
427PN Smart Energy LimitedPN$2.29-0.86%36.97K$2.95M$1.77 - $40.000.00%
428Upexi, Inc.UPXI$0.81+6.84%1.52M$71.69M$0.54 - $5.250.00%
429Alset Inc.AEI$0.53-8.25%36.69K$20.69M$0.51 - $3.980.00%
430NeuroOne Medical Technologies CorporationNMTC$0.83+1.52%36.91K$7.54M$0.77 - $6.120.00%
431HUHUTECH International Group Inc.HUHU$1.00-9.68%821.66K$25.54M$0.98 - $12.200.00%
432CollPlant Biotechnologies LtdCLGN$3.88+3.33%37.92K$7.33M$2.64 - $23.800.00%
433OSR Health, Inc.OSRH$0.12-53.28%22.28M$0$0.07 - $0.900.00%
434Geospace Technologies CorporationGEOS$4.54+3.30%34.30K$58.66M$4.11 - $29.890.00%
435Bradbury Capital Inc.BBCI$1.83+6.87%595.92K$68.84M$1.57 - $15.500.00%
436Atossa Therapeutics, Inc.ATOS$2.37-3.07%23.77K$23.60M$1.70 - $14.850.00%
437Cogent Communications Holdings, Inc.CCOI$7.48+1.49%1.64M$382.99M$7.04 - $44.310.15%
438Bone Biologics Corp.BBLG$0.37+0.77%120.47K$1.01M$0.36 - $2.390.00%
439Nyxoah SANYXH$0.90+5.22%295.77K$84.98M$0.80 - $5.920.00%
440Vivid Seats Inc.SEAT$2.19-5.56%173.68K$24.62M$2.04 - $13.870.00%
441Intelligent Bio Solutions Inc.INBS$1.70+4.27%11.05K$5.64M$1.35 - $24.900.00%
442SelectQuote, Inc.SLQT$0.35+8.04%1.02M$63.64M$0.30 - $2.220.00%
443Polar Power, Inc.POLA$0.63-10.80%174.65K$2.71M$0.57 - $4.420.00%
444DEFSEC Technologies Inc.DFSC$0.75+1.45%38.70K$3.45M$0.66 - $6.000.00%
445Quantum Biopharma LtdQNTM$2.31+4.52%86.27K$8.82M$2.07 - $14.850.00%
446Nvni Group LimitedNVNI$0.53-34.28%518.40K$5.32M$0.51 - $4.940.00%
447Terrestrial Energy Inc.IMSR$3.29+11.90%3.55M$296.62M$2.70 - $21.000.00%
448SHUTTERSTOCK, INC.SSTK$4.38-0.23%404.75K$161.83M$3.76 - $29.500.30%
449ZOOZ Strategy Ltd.ZOOZ$6.29+2.84%7.29K$51.98M$4.55 - $40.400.00%
450Granite Point Mortgage Trust Inc.GPMT$4.94+0.61%34.69K$23.28M$4.47 - $28.501.05%

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Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
Psyence Biomedical Ltd (PBM) currently shows a 52-week decline of 85.10% as of 2026-10-27 22:51 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.