Dow Jones
52,377.57
Change
+15.99+0.03%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are broadly higher today, with the Dow Jones up 0.03%, the S&P 500 up 0.60%, and the Nasdaq Composite up 1.18%. Market breadth is also positive, with 2,685 stocks advancing versus 2,433 declining, indicating a broadly bullish bias.
S&P 500
7,722.6
Change
+45.83+0.60%
Nasdaq Composite
26,477.811
Change
+308.43+1.18%
24H Gainers
2,685
24H Losers
2,433
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 4551 | DeFi Development Corp.DFDV | $3.75 | +5.04% | 984.99K | $116.09M | $2.44 - $15.10 | 0.00% |
| 4552 | ZeroStack Corp.ZSTK | $3.10 | -1.28% | 2.54K | $67.53M | $1.32 - $15.04 | 0.00% |
| 4553 | NET Power Inc.NPWR | $0.97 | +4.12% | 346.43K | $85.47M | $0.87 - $4.32 | 0.00% |
| 4554 | MicroCloud Hologram Inc.HOLO | $1.20 | +2.15% | 152.36K | $16.93M | $1.10 - $4.98 | 0.00% |
| 4555 | Lument Finance Trust, Inc.LFT | $4.23 | +1.37% | 4.88K | $22.22M | $4.14 - $17.50 | 0.64% |
| 4556 | iTonic Holdings LtdITOC | $2.54 | -1.74% | 11.19K | $17.33M | $2.33 - $18.40 | 0.00% |
| 4557 | Gaxos.ai Inc.GXAI | $0.45 | +2.27% | 55.22K | $4.94M | $0.41 - $2.63 | 0.00% |
| 4558 | BeyondSpring Inc.BYSI | $0.48 | +0.74% | 39.74K | $19.94M | $0.42 - $2.44 | 0.00% |
| 4559 | FG Nexus Inc.FGNX | $7.74 | +2.08% | 111.10K | $36.45M | $4.17 - $31.80 | 0.49% |
| 4560 | Fangdd Network Group LtdDUO | $0.58 | +0.79% | 36.92K | $22.23M | $0.42 - $2.44 | 0.00% |
| 4561 | Davion Healthcare PlcDAVI | $3.00 | -14.50% | 338.55K | $150.00M | $2.83 - $12.30 | 0.00% |
| 4562 | Cosmos Holdings Inc.COSM | $0.24 | +1.98% | 1.93M | $23.75M | $0.16 - $1.05 | 0.00% |
| 4563 | Heron Therapeutics, Inc.HRTX | $0.30 | +1.16% | 986.22K | $57.72M | $0.26 - $1.57 | 0.00% |
| 4564 | Capstone Energy Plus, Inc.CEPL | $3.06 | +9.32% | 431.60K | $86.97M | $2.54 - $12.33 | 0.00% |
| 4565 | QuantumScape CorporationQS | $4.18 | +7.44% | 15.21M | $2.46B | $3.80 - $18.56 | 0.00% |
| 4566 | BTQ Technologies Corp.BTQ | $2.23 | +8.21% | 954.43K | $334.74M | $1.81 - $10.20 | 0.00% |
| 4567 | Arq, Inc.ARQ | $1.77 | +2.59% | 140.82K | $77.51M | $1.54 - $7.03 | 0.00% |
| 4568 | Nexus Advanced Technologies Inc.NXAT | $0.34 | +3.53% | 132.12K | $1.24M | $0.33 - $1.50 | 0.00% |
| 4569 | Xanadu Quantum Technologies LimitedXNDU | $2.94 | +14.65% | 4.61M | $803.60M | $2.50 - $42.44 | 0.00% |
| 4570 | Greenland Energy CompanyGLND | $3.32 | +6.07% | 1.98M | $131.19M | $1.09 - $23.00 | 0.00% |
| 4571 | Evommune, Inc.EVMN | $5.15 | +0.58% | 1.23M | $185.09M | $4.94 - $33.20 | 0.00% |
| 4572 | Gogo Inc.GOGO | $2.38 | +8.68% | 1.58M | $321.83M | $1.96 - $9.93 | 0.00% |
| 4573 | Heartbeam, Inc.BEAT | $0.41 | -1.00% | 1.18M | $22.82M | $0.35 - $4.00 | 0.00% |
| 4574 | Aclarion, Inc.ACON | $1.92 | +1.04% | 2.40K | $5.53M | $1.85 - $9.36 | 0.00% |
| 4575 | Incannex Healthcare LimitedIXHL | $2.63 | +0.38% | 64.30K | $33.06M | $2.49 - $14.91 | 0.00% |
| 4576 | Eva Live Inc.GOAI | $1.00 | -0.74% | 321.32K | $40.39M | $0.97 - $18.00 | 0.00% |
| 4577 | NervGen Pharma Corp.NGEN | $1.48 | +3.52% | 525.45K | $119.58M | $1.37 - $6.30 | 0.00% |
| 4578 | XCEL BRANDS INC.XELB | $0.33 | -4.57% | 9.62K | $2.31M | $0.27 - $2.47 | 0.00% |
| 4579 | Vital Farms, Inc.VITL | $9.05 | +1.06% | 1.46M | $388.53M | $7.95 - $38.64 | 0.00% |
| 4580 | Basel Medical Group LtdBMGL | $4.61 | +1.32% | 1.06M | $7.30M | $2.56 - $19.80 | 0.00% |
| 4581 | Ambitions Enterprise Management Co. L.L.CAHMA | $1.09 | +0.93% | 11.78K | $33.44M | $0.76 - $39.50 | 0.00% |
| 4582 | Gaia, Inc.GAIA | $1.38 | +7.84% | 94.26K | $27.56M | $1.16 - $5.95 | 0.00% |
| 4583 | Tenaya Therapeutics, Inc.TNYA | $0.41 | -0.91% | 2.10M | $90.81M | $0.36 - $1.70 | 0.00% |
| 4584 | Corbus Pharmaceuticals Holdings, Inc.CRBP | $4.15 | +4.01% | 623.89K | $77.45M | $3.87 - $18.11 | 0.00% |
| 4585 | Pulsenmore Ltd.PLSM | $1.79 | +4.05% | 5.70K | $11.51M | $1.69 - $12.97 | 0.00% |
| 4586 | WEBUY GLOBAL LTDWBUY | $0.61 | -5.01% | 134.15K | $3.19M | $0.58 - $4.96 | 0.00% |
| 4587 | Greenland Mines LtdGRML | $5.69 | -1.55% | 1.24M | $68.41M | $2.82 - $27.48 | 0.00% |
| 4588 | Opendoor Technologies Inc.OPEN | $1.92 | -0.78% | 30.44M | $1.85B | $1.84 - $9.15 | 0.00% |
| 4589 | Arbor Realty Trust, Inc.ABR | $2.88 | -0.35% | 9.48M | $538.22M | $2.53 - $11.95 | 0.49% |
| 4590 | Banzai International, Inc.PARA | $4.25 | +10.70% | 816.12K | $21.50M | $1.09 - $19.40 | 0.00% |
| 4591 | SEALSQ Corp.LAES | $1.64 | +7.57% | 4.02M | $313.14M | $1.50 - $7.64 | 0.00% |
| 4592 | Golden Heaven Group Holdings LtdGDHG | $1.12 | -2.61% | 132.75K | $66.61M | $1.04 - $5.31 | 0.00% |
| 4593 | Sable Offshore Corp.SOC | $3.08 | -1.60% | 4.23M | $590.96M | $2.88 - $19.25 | 0.00% |
| 4594 | Mustang Bio, Inc.MBIO | $0.36 | +0.62% | 24.87K | $2.42M | $0.36 - $1.52 | 0.00% |
| 4595 | Atlas Critical Minerals CorporationATCX | $2.10 | -0.47% | 13.95K | $9.28M | $2.02 - $14.01 | 0.00% |
| 4596 | Maris-Tech Ltd.MTEK | $0.41 | -1.22% | 85.36K | $3.95M | $0.37 - $2.82 | 0.00% |
| 4597 | Magic Empire Global LimitedMEGL | $0.33 | -54.22% | 35.21M | $51.48M | $0.23 - $1.64 | 0.00% |
| 4598 | SoundHound AI, Inc.SOUN | $4.37 | +3.07% | 16.56M | $1.80B | $4.20 - $19.09 | 0.00% |
| 4599 | DocGo Inc.DCGO | $0.27 | -4.73% | 365.15K | $26.81M | $0.24 - $1.20 | 0.00% |
| 4600 | BridgeBio Oncology Therapeutics, Inc.BBOT | $2.69 | +1.70% | 1.66M | $213.26M | $2.51 - $14.87 | 0.00% |
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| Position types | Buy and hold | Buy and hold | Long, short, leveraged |
| Best for | Long-term investors seeking ownership and dividend income | Traders wanting round-the-clock access to stock exposure without holding shares | Active/short-term traders looking to speculate or hedge with leverage |
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
DeFi Development Corp. (DFDV) currently leads with a 52-week gain of 73.74% as of 2026-10-27 23:17 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
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Nvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBVNvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBVNvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBVNvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBV
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Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.