52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview

U.S. stocks are broadly higher today, with the Dow Jones up ⁦0.03%⁩, the S&P 500 up ⁦0.60%⁩, and the Nasdaq Composite up ⁦1.18%⁩. Market breadth is also positive, with 2,689 stocks advancing versus 2,429 declining, indicating a broadly bullish bias.

Dow Jones

52,377.57

Change

+15.99+0.03%

S&P 500

7,722.6

Change

+45.83+0.60%

Nasdaq Composite

26,477.811

Change

+308.43+1.18%

24H Gainers

2,689

24H Losers

2,429

52 Week Gainers

Large Cap Small Cap 52 Week Gainers 52 Week Losers Semiconductor Software Biotech Bank

#	Stock					52 Week Range
4651	Reliance Global Group, Inc.EZRA	$2.24	-2.24%	10.13K	$3.76M	$1.75 - $17.20	0.14%
4652	Aurelion Inc.AURE	$1.02	-11.43%	73.52K	$19.73M	$0.85 - $5.62	0.00%
4653	Lexaria Bioscience Corp.LEXX	$3.10	+6.85%	39.51K	$6.54M	$2.43 - $21.60	0.00%
4654	Serve Robotics Inc.SERV	$2.94	+11.74%	3.89M	$254.49M	$2.63 - $16.08	0.00%
4655	Beeline Holdings, Inc.BLNE	$0.71	+7.83%	436.60K	$23.03M	$0.61 - $3.75	0.00%
4656	Ensysce Biosciences, Inc.ENSC	$0.44	-3.08%	397.50K	$8.56M	$0.23 - $2.25	0.00%
4657	Aptera Motors Corp.SEV	$1.60	+3.90%	175.50K	$61.81M	$1.29 - $9.99	0.00%
4658	First Breach Inc.FBDT	$0.85	+4.76%	148.16K	$41.83M	$0.61 - $12.00	0.00%
4659	ASP Isotopes Inc.ASPI	$2.06	+2.23%	3.99M	$316.58M	$1.89 - $11.22	0.00%
4660	Australian Oilseeds Holdings LimitedCOOT	$0.35	-8.40%	29.52K	$9.74M	$0.32 - $1.95	0.00%
4661	Tevogen Inc.TVGN	$6.38	+1.34%	5.13K	$100.32M	$3.64 - $32.90	0.00%
4662	Galaxy Payroll Group LimitedGLXG	$0.86	+0.58%	23.54K	$5.19M	$0.72 - $4.79	0.00%
4663	High-Trend International GroupHTCO	$1.80	+13.84%	801.78K	$13.87M	$0.90 - $56.59	0.00%
4664	InspireMD, Inc.NSPR	$0.46	+1.56%	390.58K	$21.15M	$0.43 - $2.41	0.00%
4665	Natural Health Trends Corp.NHTC	$0.88	-7.55%	73.63K	$7.57M	$0.78 - $4.60	0.83%
4666	Teads Holding CoTEAD	$0.34	+6.73%	473.68K	$33.83M	$0.33 - $1.82	0.00%
4667	Avax One Technology LtdAVX	$4.39	-2.12%	346.97K	$32.51M	$2.81 - $31.80	0.00%
4668	Armlogi Holding Corp.BTOC	$2.13	-5.33%	3.75K	$6.05M	$2.13 - $11.69	0.00%
4669	Baird Medical Investment Holdings LtdBDMD	$0.29	-35.12%	1.48M	$12.07M	$0.22 - $3.70	0.00%
4670	Oklo Inc.OKLO	$27.33	+5.02%	7.09M	$5.08B	$25.39 - $152.06	0.00%
4671	AETHLON MEDICAL INC.AEMD	$5.09	-2.60%	23.33K	$3.62M	$1.41 - $29.45	0.00%
4672	Workhorse Group, Inc.WKHS	$2.56	+0.39%	30.87K	$27.98M	$2.31 - $13.32	0.00%
4673	enGene Therapeutics Inc.ENGN	$1.55	-1.90%	338.36K	$104.21M	$1.40 - $12.25	0.00%
4674	Nuran Wireless Inc.NUR	$0.68	-5.87%	30.50K	$8.90M	$0.60 - $7.72	0.00%
4675	Barfresh Food Group Inc.BRFH	$0.63	+4.17%	41.53K	$10.19M	$0.56 - $3.50	0.00%
4676	Enveric Biosciences, Inc.ENVB	$1.43	+3.62%	55.83K	$6.41M	$1.17 - $13.25	0.00%
4677	OneMedNet Corp.ONMD	$4.42	+1.34%	21.43K	$26.19M	$3.61 - $24.60	0.00%
4678	York Space Systems Inc.YSS	$6.50	+2.06%	926.42K	$866.73M	$5.52 - $44.54	0.00%
4679	Dogwood Therapeutics, Inc.DWTX	$1.16	+5.41%	13.04K	$39.43M	$1.07 - $7.04	0.00%
4680	Context Therapeutics Inc.CNTX	$0.24	-1.46%	1.64M	$21.68M	$0.22 - $3.62	0.00%
4681	Defi Technologies, Inc.DEFT	$0.40	+3.29%	1.28M	$155.30M	$0.38 - $2.13	0.00%
4682	Aqua Metals, Inc.AQMS	$1.49	+1.36%	13.00K	$5.32M	$1.37 - $11.48	0.00%
4683	Fort Technology Inc.FRTT	$0.65	-3.74%	139.69K	$9.83M	$0.50 - $4.09	0.00%
4684	Hadron Energy, Inc.HDRN	$0.77	-11.48%	177.96K	$54.98M	$0.60 - $5.40	0.00%
4685	loanDepot, Inc.LDI	$0.66	+13.76%	2.73M	$151.77M	$0.48 - $3.58	0.00%
4686	Elicio Therapeutics, Inc.ELTX	$1.83	+8.24%	326.19K	$49.58M	$1.44 - $16.00	0.00%
4687	Tilray Brands, Inc.TLRY	$2.77	+1.84%	2.27M	$408.63M	$2.68 - $15.70	0.00%
4688	Longeveron Inc.LGVN	$1.73	+7.79%	90.48K	$5.25M	$1.31 - $12.30	0.00%
4689	Caribou Biosciences, Inc.CRBU	$0.46	-6.77%	2.23M	$49.32M	$0.44 - $3.54	0.00%
4690	Upland Software, Inc.UPLD	$3.98	+0.38%	44.75K	$11.76M	$2.75 - $22.00	0.00%
4691	ZenaTech, Inc.ZENA	$0.92	+2.08%	1.98M	$184.86M	$0.86 - $5.17	0.00%
4692	Dermata Therapeutics, Inc.DRMA	$0.76	-5.13%	186.42K	$3.76M	$0.60 - $4.66	0.00%
4693	Research Frontiers Inc.REFR	$0.44	-1.35%	15.35K	$15.34M	$0.34 - $2.70	0.00%
4694	LanzaTech Global, Inc.LNZA	$4.99	+4.20%	53.38K	$65.31M	$4.29 - $44.00	0.00%
4695	Deep Fission, Inc.FISN	$2.70	+25.46%	587.53K	$135.48M	$2.10 - $19.00	0.00%
4696	Lucid Group, Inc.LCID	$3.31	-2.65%	10.29M	$1.31B	$2.37 - $19.48	0.00%
4697	Imunon, Inc.IMNN	$0.86	-30.06%	523.20K	$4.84M	$0.84 - $4.90	0.00%
4698	Corteva, Inc.CTVA	$11.63	-1.34%	11.03M	$7.76B	$11.63 - $90.97	0.06%
4699	Compass Therapeutics, Inc.CMPX	$0.75	+0.62%	1.66M	$134.53M	$0.73 - $6.88	0.00%
4700	FuboTV Inc.FUBO	$7.81	+0.26%	1.36M	$235.80M	$7.55 - $52.68	0.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?

These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.

How is the 52-week gain calculated?

It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.

Which stock has gained the most over 52 weeks?

Reliance Global Group, Inc. (EZRA) currently leads with a 52-week gain of 79.23% as of 2026-10-27 22:33 UTC.

Why use a 52-week stock performance ranking?

It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.

Does strong 52-week performance guarantee future gains?

No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.

How is this different from the daily Top Gainers list?

The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.