Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More
0-Fee Fest

52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are broadly higher today, with the Dow Jones up ⁦0.10%⁩, the S&P 500 up ⁦0.67%⁩, and the Nasdaq Composite up ⁦1.28%⁩. Market breadth is also positive, with 2,572 stocks advancing versus 2,546 declining, indicating a broadly bullish bias.

Dow Jones
52,413.68
Change
+52.1+0.10%
S&P 500
7,727.89
Change
+51.12+0.67%
Nasdaq Composite
26,505.315
Change
+335.934+1.28%
24H Gainers
2,572
24H Losers
2,546

52 Week Losers

#Stock52 Week Range
551Expion Energy, Inc.XPON$3.75+2.54%4.46K$3.80M$2.77 - $19.200.00%
552Locafy LimitedLCFY$1.15-0.43%10.35K$2.58M$1.10 - $6.200.00%
553Bit Digital, Inc.BTBT$0.92+9.49%29.76M$331.06M$0.81 - $4.080.00%
554Ainos, Inc.AIMD$0.83+2.47%4.82K$6.13M$0.67 - $3.880.00%
555Tenax Therapeutics, Inc.TENX$1.73+6.10%1.42M$64.78M$1.31 - $19.400.00%
556Soligenix, Inc.SNGX$0.36+2.83%73.41K$7.84M$0.28 - $1.700.00%
557Big Tree Cloud Holdings LimitedDSY$3.33+0.73%2.13K$15.92M$1.67 - $19.900.00%
558Tactical Resources Corp.TREO$1.67+15.90%87.38K$20.55M$1.40 - $9.200.00%
559Super League Enterprise, Inc.SLE$5.19-6.35%95.23K$8.80M$2.12 - $24.360.00%
560Processa Pharmaceuticals, Inc.PCSA$1.82+0.28%13.27K$5.11M$1.04 - $10.840.00%
561Exicure, Inc.XCUR$1.10+0.92%12.07K$7.21M$0.94 - $9.480.00%
562One and One Green Technologies. Inc.YDDL$1.20+0.75%12.35K$68.36M$1.08 - $16.230.00%
563Cuprina Holdings (Cayman) LimitedCUPR$1.83+0.56%274.32K$9.59M$1.45 - $14.800.00%
564Alpha Compute Corp.ALP$3.31+11.24%18.30K$5.13M$2.78 - $27.900.00%
565The Trade Desk, Inc.TTD$12.71-0.51%7.11M$5.46B$11.62 - $54.050.00%
566Fervo Energy CompanyFRVO$8.67+8.91%5.29M$2.37B$7.72 - $42.650.00%
567BridgeBio Oncology Therapeutics, Inc.BBOT$2.69+1.70%1.66M$213.26M$2.51 - $14.870.00%
568DocGo Inc.DCGO$0.27-4.73%365.15K$26.81M$0.24 - $1.200.00%
569SoundHound AI, Inc.SOUN$4.37+3.07%16.56M$1.80B$4.20 - $19.090.00%
570Magic Empire Global LimitedMEGL$0.33-54.22%35.21M$51.48M$0.23 - $1.640.00%
571Atlas Critical Minerals CorporationATCX$2.10-0.47%13.95K$9.28M$2.02 - $14.010.00%
572Maris-Tech Ltd.MTEK$0.41-1.22%85.36K$3.95M$0.37 - $2.820.00%
573Mustang Bio, Inc.MBIO$0.36+0.62%24.87K$2.42M$0.36 - $1.520.00%
574Sable Offshore Corp.SOC$3.08-1.28%4.23M$590.96M$2.88 - $19.250.00%
575Golden Heaven Group Holdings LtdGDHG$1.12-2.61%132.75K$66.61M$1.04 - $5.310.00%
576SEALSQ Corp.LAES$1.64+7.57%4.02M$313.14M$1.50 - $7.640.00%
577Banzai International, Inc.PARA$4.25+10.70%816.12K$21.50M$1.09 - $19.400.00%
578Arbor Realty Trust, Inc.ABR$2.88-0.35%9.48M$538.22M$2.53 - $11.950.49%
579Opendoor Technologies Inc.OPEN$1.92-0.78%30.44M$1.85B$1.84 - $9.150.00%
580Greenland Mines LtdGRML$5.69-1.55%1.24M$68.41M$2.82 - $27.480.00%
581WEBUY GLOBAL LTDWBUY$0.61-5.01%134.15K$3.19M$0.58 - $4.960.00%
582Corbus Pharmaceuticals Holdings, Inc.CRBP$4.15+4.01%623.89K$77.45M$3.87 - $18.110.00%
583Pulsenmore Ltd.PLSM$1.79+4.05%5.70K$11.51M$1.69 - $12.970.00%
584Tenaya Therapeutics, Inc.TNYA$0.41-0.91%2.10M$90.81M$0.36 - $1.700.00%
585Gaia, Inc.GAIA$1.38+7.84%94.26K$27.56M$1.16 - $5.950.00%
586Ambitions Enterprise Management Co. L.L.CAHMA$1.09+0.93%11.78K$33.44M$0.76 - $39.500.00%
587Basel Medical Group LtdBMGL$4.61+1.32%1.06M$7.30M$2.56 - $19.800.00%
588Vital Farms, Inc.VITL$9.05+1.06%1.46M$388.53M$7.95 - $38.640.00%
589XCEL BRANDS INC.XELB$0.33-4.57%9.62K$2.31M$0.27 - $2.470.00%
590NervGen Pharma Corp.NGEN$1.48+3.52%525.45K$119.58M$1.37 - $6.300.00%
591Eva Live Inc.GOAI$1.00-0.74%321.32K$40.39M$0.97 - $18.000.00%
592Incannex Healthcare LimitedIXHL$2.63+0.38%64.30K$33.06M$2.49 - $14.910.00%
593Aclarion, Inc.ACON$1.92+1.04%2.40K$5.53M$1.85 - $9.360.00%
594Heartbeam, Inc.BEAT$0.41-1.00%1.18M$22.82M$0.35 - $4.000.00%
595Gogo Inc.GOGO$2.38+8.68%1.58M$321.83M$1.96 - $9.930.00%
596Evommune, Inc.EVMN$5.15+0.58%1.23M$185.09M$4.94 - $33.200.00%
597Greenland Energy CompanyGLND$3.32+6.07%1.98M$131.19M$1.09 - $23.000.00%
598Xanadu Quantum Technologies LimitedXNDU$2.94+14.65%4.61M$803.60M$2.50 - $42.440.00%
599Nexus Advanced Technologies Inc.NXAT$0.34+3.53%132.12K$1.24M$0.33 - $1.500.00%
600Arq, Inc.ARQ$1.77+2.59%140.82K$77.51M$1.54 - $7.030.00%

Deposit USD for Up to $520

First USD deposit earns $20 with 0 fees

Deposit USD for Up to $520

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
Expion Energy, Inc. (XPON) currently shows a 52-week decline of 77.00% as of 2026-10-28 01:44 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.