52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview
U.S. stocks are mixed today. The Dow Jones is -0.06%, the S&P 500 is +0.51%, and the Nasdaq Composite is +1.09%. Across individual stocks, 2,396 are advancing while 2,720 are declining, suggesting a mixed market tone.
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 51 | RF Acquisition Corp IIRFAI | $32.86 | -10.69% | 6.33K | $115.43M | $8.94 - $73.00 | 0.00% |
| 52 | MBX Biosciences, Inc.MBX | $52.80 | +4.99% | 119.39K | $2.54B | $16.91 - $72.64 | 0.00% |
| 53 | Western Digital Corp.WDC | $382.12 | +7.34% | 5.81M | $143.04B | $121.85 - $799.87 | 0.00% |
| 54 | Pulse Biosciences, Inc.PLSE | $52.70 | +0.53% | 155.80K | $3.73B | $12.56 - $58.90 | 0.00% |
| 55 | Seagate Technology Holdings PLCSTX | $674.29 | +4.87% | 4.54M | $153.33B | $217.67 - $1,145.00 | 0.00% |
| 56 | Bandwidth Inc.BAND | $49.57 | +4.94% | 290.05K | $1.50B | $12.50 - $79.08 | 0.00% |
| 57 | Forum Energy Technologies, Inc.FET | $90.11 | +1.27% | 47.82K | $1.01B | $26.00 - $91.53 | 0.00% |
| 58 | Tango Therapeutics, Inc.TNGX | $22.55 | +2.48% | 1.48M | $3.80B | $7.12 - $34.39 | 0.00% |
| 59 | Fossil Group, Inc.FOSL | $6.56 | +2.18% | 209.13K | $387.95M | $1.70 - $7.39 | 0.00% |
| 60 | RINGCENTRAL, INC.RNG | $86.35 | +0.16% | 730.28K | $6.45B | $24.14 - $98.14 | 0.00% |
| 61 | Okeanis Eco Tankers Corp.ECO | $94.29 | -2.83% | 484.91K | $3.70B | $31.75 - $100.68 | 0.00% |
| 62 | Lindblad Expeditions Holdings Inc.LIND | $35.62 | +2.74% | 271.64K | $2.34B | $11.37 - $36.97 | 0.00% |
| 63 | Vera Bradley, Inc.VRA | $6.13 | +3.19% | 224.48K | $175.89M | $1.39 - $6.43 | 0.00% |
| 64 | Vestis CorporationVSTS | $15.04 | +0.27% | 585.03K | $1.99B | $4.83 - $16.90 | 0.00% |
| 65 | Illumina Inc.ILMN | $281.07 | +3.50% | 977.03K | $42.44B | $94.00 - $309.35 | 0.00% |
| 66 | Nuvectis Pharma, Inc.NVCT | $18.20 | +0.16% | 72.38K | $594.12M | $5.55 - $29.27 | 0.00% |
| 67 | Shattuck Labs, Inc.STTK | $5.72 | +3.61% | 206.61K | $574.08M | $1.72 - $8.33 | 0.00% |
| 68 | Syntec Optics Holdings, Inc.OPTX | $7.03 | +6.10% | 91.06K | $282.97M | $1.18 - $14.92 | 0.00% |
| 69 | Marvell Technology, Inc.MRVL | $242.68 | +3.79% | 8.43M | $212.81B | $70.69 - $329.88 | 0.00% |
| 70 | StablecoinX Inc.USDE | $10.10 | -4.82% | 507.42K | $251.11M | $1.33 - $18.11 | 0.00% |
| 71 | AN2 Therapeutics, Inc.ANTX | $3.67 | +0.69% | 124.84K | $138.30M | $1.00 - $7.19 | 0.00% |
| 72 | Eton Pharmaceutcials, Inc.ETON | $49.90 | -1.43% | 126.42K | $1.43B | $14.27 - $66.37 | 0.00% |
| 73 | Andersen Group Inc.ANDG | $63.20 | -1.42% | 68.26K | $1.18B | $18.12 - $65.94 | 0.00% |
| 74 | DigitalOcean Holdings, Inc.DOCN | $107.66 | +7.94% | 1.54M | $11.24B | $37.84 - $187.50 | 0.00% |
| 75 | Aura Minerals Inc.AUGO | $80.98 | +5.41% | 304.04K | $6.79B | $29.11 - $110.32 | 0.00% |
| 76 | Globus Maritime LimitedGLBS | $2.99 | +0.37% | 48.11K | $64.55M | $1.04 - $4.06 | 0.00% |
| 77 | Pyxis Tankers Inc.PXS | $7.21 | -4.50% | 88.90K | $73.79M | $2.56 - $8.34 | 0.00% |
| 78 | Penguin Solutions, Inc.PENG | $59.32 | +7.85% | 1.30M | $3.57B | $16.04 - $89.86 | 0.00% |
| 79 | LifeStance Health Group, Inc.LFST | $13.07 | -0.34% | 1.01M | $5.00B | $4.77 - $13.56 | 0.00% |
| 80 | Hyperliquid Strategies Inc.PURR | $9.93 | +10.58% | 7.06M | $1.74B | $3.01 - $14.76 | 0.00% |
| 81 | Iridium Communications Inc.IRDM | $45.69 | +3.07% | 251.47K | $4.85B | $15.64 - $57.18 | 0.01% |
| 82 | NGL ENERGY PARTNERS LPNGL | $16.12 | +1.64% | 15.72K | $2.01B | $6.26 - $19.06 | 0.05% |
| 83 | TOP Financial Group LimitedTOP | $15.33 | +0.79% | 119.53K | $1.87B | $3.06 - $17.42 | 0.00% |
| 84 | Relay Therapeutics, Inc.RLAY | $18.65 | +2.81% | 1.01M | $4.09B | $5.95 - $21.27 | 0.00% |
| 85 | Ethos Technologies Inc.LIFE | $42.44 | +0.71% | 595.08K | $2.80B | $9.45 - $44.99 | 0.00% |
| 86 | Okta, Inc.OKTA | $226.58 | +2.99% | 1.33M | $37.87B | $62.66 - $235.00 | 0.00% |
| 87 | Aehr Test SystemsAEHR | $63.28 | +12.55% | 1.61M | $2.07B | $18.70 - $147.40 | 0.00% |
| 88 | Hewlett Packard Enterprise CompanyHPE | $60.84 | +3.56% | 6.55M | $80.76B | $19.84 - $73.56 | 0.01% |
| 89 | FIGS, Inc.FIGS | $20.50 | -1.34% | 1.16M | $3.24B | $7.21 - $20.89 | 0.00% |
| 90 | Guardant Health, Inc.GH | $177.70 | +2.02% | 655.64K | $23.85B | $68.02 - $191.05 | 0.00% |
| 91 | Paysign, Inc.PAYS | $14.60 | +3.26% | 350.42K | $824.35M | $3.08 - $16.15 | 0.00% |
| 92 | Able View Global Inc.ABLV | $2.36 | +1.98% | 84.26K | $57.84M | $0.54 - $2.86 | 0.00% |
| 93 | Tilly's Inc.TLYS | $4.20 | -0.24% | 74.50K | $97.69M | $1.14 - $6.25 | 0.00% |
| 94 | Edgewise Therapeutics, Inc.EWTX | $39.53 | +1.28% | 279.76K | $4.29B | $15.23 - $48.51 | 0.00% |
| 95 | Calumet, Inc.CLMT | $49.52 | -4.64% | 624.97K | $4.35B | $17.85 - $59.87 | 0.00% |
| 96 | First Tracks Biotherapeutics, Inc.TRAX | $45.70 | +5.24% | 328.38K | $1.57B | $14.72 - $49.91 | 0.00% |
| 97 | FormFactor Inc.FORM | $106.80 | +5.85% | 611.48K | $8.33B | $41.84 - $160.27 | 0.00% |
| 98 | Hongli Group Inc.HLP | $3.56 | +1.00% | 190.89K | $266.07M | $0.34 - $3.63 | 0.00% |
| 99 | Glaukos CorporationGKOS | $183.54 | +3.12% | 776.82K | $10.83B | $73.16 - $191.62 | 0.00% |
| 100 | Maravai LifeSciences Holdings, Inc.MRVI | $8.10 | +7.39% | 972.99K | $1.21B | $2.54 - $9.42 | 0.00% |
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
How is the 52-week gain calculated?
Which stock has gained the most over 52 weeks?
Why use a 52-week stock performance ranking?
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How is this different from the daily Top Gainers list?
Discover Top US Stocks
Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.






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