Dow Jones
52,396.13
Change
+34.55+0.07%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are mixed today. The Dow Jones is +0.07%, the S&P 500 is +0.57%, and the Nasdaq Composite is +1.12%. Across individual stocks, 2,435 are advancing while 2,682 are declining, suggesting a mixed market tone.
S&P 500
7,720.15
Change
+43.38+0.57%
Nasdaq Composite
26,463.622
Change
+294.241+1.12%
24H Gainers
2,435
24H Losers
2,682
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 101 | Definium Therapeutics, Inc.DFTX | $37.27 | +5.21% | 656.16K | $5.01B | $14.62 - $49.70 | 0.00% |
| 102 | American Well CorporationAMWL | $13.36 | -1.03% | 17.43K | $201.25M | $3.71 - $14.56 | 0.00% |
| 103 | American Outdoor Brands, Inc.AOUT | $17.77 | -1.22% | 42.06K | $224.28M | $6.26 - $18.62 | 0.00% |
| 104 | Hycroft Mining Holding CorporationHYMC | $16.32 | +6.69% | 1.23M | $1.52B | $6.48 - $58.73 | 0.00% |
| 105 | Silicom LtdSILC | $42.03 | +5.69% | 66.02K | $241.59M | $13.34 - $63.00 | 0.00% |
| 106 | Viavi Solutions Inc.VIAV | $33.56 | +5.49% | 1.44M | $8.25B | $13.74 - $60.43 | 0.00% |
| 107 | Tower Semiconductor LtdTSEM | $189.13 | +6.17% | 1.05M | $19.02B | $77.04 - $319.94 | 0.00% |
| 108 | Century Therapeutics, Inc.IPSC | $1.44 | +2.46% | 234.44K | $259.84M | $0.43 - $3.04 | 0.00% |
| 109 | DHI Group, Inc.DHX | $4.86 | +4.29% | 84.31K | $211.17M | $1.44 - $5.19 | 0.00% |
| 110 | Noodles & CompanyNDLS | $13.45 | -0.07% | 9.98K | $80.22M | $3.57 - $19.00 | 0.00% |
| 111 | Matsons, Inc.MATX | $232.43 | +1.51% | 83.29K | $6.95B | $94.19 - $240.87 | 0.01% |
| 112 | Intel Corp.INTC | $93.73 | +3.71% | 58.42M | $472.78B | $32.89 - $142.35 | 0.00% |
| 113 | LB Pharmaceuticals Inc.LBRX | $39.51 | +0.70% | 116.59K | $1.25B | $14.32 - $50.16 | 0.00% |
| 114 | Dianthus Therapeutics, Inc.DNTH | $79.17 | +0.47% | 307.65K | $4.34B | $32.28 - $117.88 | 0.00% |
| 115 | Absci CorporationABSI | $10.60 | +11.27% | 3.30M | $1.82B | $2.24 - $12.05 | 0.00% |
| 116 | Immix Biopharma, Inc.IMMX | $7.98 | -0.62% | 536.21K | $570.88M | $2.85 - $15.10 | 0.00% |
| 117 | Baytex Energy Corp.BTE | $5.46 | -1.63% | 12.55M | $3.77B | $2.23 - $5.60 | 0.00% |
| 118 | Fortrea Holdings Inc.FTRE | $24.37 | +2.14% | 912.48K | $2.32B | $8.55 - $26.80 | 0.00% |
| 119 | Haemonetics CorporationHAE | $119.93 | +0.42% | 352.65K | $5.46B | $48.98 - $123.77 | 0.00% |
| 120 | Vicor Corp.VICR | $209.62 | +7.67% | 575.44K | $7.21B | $80.29 - $382.65 | 0.00% |
| 121 | Tsakos Energy Navigation Ltd.TEN | $53.98 | -2.16% | 194.09K | $1.63B | $21.65 - $56.73 | 0.00% |
| 122 | International Seaways, Inc.INSW | $112.71 | -0.90% | 326.59K | $5.58B | $46.09 - $126.27 | 0.07% |
| 123 | Kelly Services Inc.KELYB | $27.02 | +3.54% | 2.92K | $89.08M | $8.38 - $125.00 | 0.01% |
| 124 | Frontline PlcFRO | $54.38 | -1.69% | 1.91M | $12.11B | $20.47 - $59.75 | 0.00% |
| 125 | Marex Group LimitedMRX | $69.88 | -1.24% | 128.63K | $5.03B | $29.91 - $79.11 | 0.00% |
| 126 | Hinge Health, Inc.HNGE | $113.00 | +0.95% | 642.38K | $9.00B | $30.08 - $113.48 | 0.00% |
| 127 | Encore Capital Group, Inc.ECPG | $100.58 | +0.63% | 46.23K | $2.13B | $40.52 - $105.98 | 0.00% |
| 128 | Abercrombie & Fitch Co.ANF | $166.84 | +1.38% | 721.21K | $7.08B | $65.45 - $167.15 | 0.00% |
| 129 | Marwynn Holdings, Inc.MWYN | $2.25 | -3.42% | 266.47K | $48.67M | $0.45 - $2.71 | 0.00% |
| 130 | Elite Express Holding Inc.ETS | $1.65 | -3.80% | 48.58K | $107.37M | $0.39 - $2.75 | 0.00% |
| 131 | Valero Energy CorporationVLO | $391.14 | -7.93% | 2.77M | $112.62B | $159.90 - $461.52 | 0.01% |
| 132 | MARATHON PETROLEUM CORPORATIONMPC | $438.71 | -6.48% | 1.53M | $128.08B | $161.93 - $493.98 | 0.01% |
| 133 | Lifetime Brands, Inc.LCUT | $8.38 | +1.57% | 43.82K | $192.65M | $2.90 - $10.17 | 0.02% |
| 134 | Prelude Therapeutics IncorporatedPRLD | $3.82 | +3.78% | 83.72K | $304.85M | $1.17 - $6.83 | 0.00% |
| 135 | Smart Sand, Inc.SND | $4.98 | +2.48% | 54.39K | $211.15M | $2.08 - $5.92 | 0.05% |
| 136 | Omeros CorporationOMER | $17.18 | +6.05% | 393.56K | $1.24B | $6.24 - $21.24 | 0.00% |
| 137 | PBF ENERGY INC.PBF | $74.39 | -7.27% | 1.46M | $8.82B | $25.62 - $92.46 | 0.01% |
| 138 | AMN Healthcare ServicesAMN | $46.69 | -4.84% | 651.67K | $1.81B | $14.97 - $49.59 | 0.00% |
| 139 | GridAI Technologies Corp.GRDX | $5.50 | -1.62% | 64.37K | $39.23M | $1.87 - $6.93 | 0.00% |
| 140 | Usio, Inc.USIO | $3.19 | +3.23% | 79.94K | $90.96M | $1.03 - $3.29 | 0.00% |
| 141 | Nurix Therapeutics, Inc.NRIX | $26.54 | +3.87% | 1.12M | $2.90B | $11.19 - $28.23 | 0.00% |
| 142 | Twilio Inc.TWLO | $253.47 | -3.24% | 906.86K | $38.93B | $105.00 - $308.40 | 0.00% |
| 143 | Teradyne, Inc.TER | $326.33 | +5.66% | 1.45M | $51.02B | $144.11 - $487.91 | 0.00% |
| 144 | AbCellera Biologics Inc.ABCL | $12.75 | +5.22% | 2.03M | $3.91B | $2.75 - $15.02 | 0.00% |
| 145 | Anika Therapeutics Inc.ANIK | $21.36 | +0.61% | 22.12K | $285.91M | $9.01 - $22.88 | 0.00% |
| 146 | Hamilton Beach Brands Holding CompanyHBB | $32.02 | -3.67% | 18.56K | $315.71M | $13.75 - $39.99 | 0.01% |
| 147 | Nordic American TankerNAT | $7.86 | -0.82% | 1.99M | $1.66B | $3.33 - $8.88 | 0.00% |
| 148 | Kiniksa Pharmaceuticals International, plcKNSA | $88.97 | +24.16% | 1.44M | $4.30B | $35.20 - $90.72 | 0.00% |
| 149 | Karat Packaging Inc.KRT | $54.49 | -0.40% | 83.64K | $1.09B | $20.61 - $56.06 | 0.03% |
| 150 | Cohu Inc.COHU | $51.11 | +4.65% | 455.46K | $2.42B | $21.10 - $75.72 | 0.00% |
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Definium Therapeutics, Inc. (DFTX) currently leads with a 52-week gain of 142.31% as of 2026-10-27 17:50 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
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Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.