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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦0.00%⁩, the S&P 500 is ⁦+0.53%⁩, and the Nasdaq Composite is ⁦+1.09%⁩. Across individual stocks, 2,493 are advancing while 2,624 are declining, suggesting a mixed market tone.

Dow Jones
52,363.79
Change
+2.210.00%
S&P 500
7,717.39
Change
+40.62+0.53%
Nasdaq Composite
26,454.159
Change
+284.778+1.09%
24H Gainers
2,493
24H Losers
2,624

52 Week Gainers

#Stock52 Week Range
4901Nexentis Technologies Inc.NXTS$0.57+0.69%129.81K$1.69M$0.50 - $23.800.00%
4902Senti Biosciences Holdings, Inc.SNTI$0.18+2.86%54.79M$5.87M$0.16 - $2.880.00%
4903Murano Global Investments PLCMRNO$0.22-1.00%133.04K$17.37M$0.18 - $2.910.00%
4904bioAffinity Technologies, Inc.BIAF$2.99+9.54%183.79K$1.80M$2.66 - $80.700.00%
4905ICZOOM Group Inc.IZM$0.76+4.54%7.44K$1.24M$0.71 - $13.650.00%
4906Golden Sun Technology Group LimitedGSUN$0.18+0.52%77.39K$1.71M$0.17 - $2.420.00%
4907Concorde International Group LtdCIGL$0.21-1.50%57.94K$43.61M$0.20 - $3.760.00%
4908Flux Power Holdings, Inc.FLUX$0.41+1.66%42.88K$8.97M$0.39 - $6.400.00%
4909Smart Logistics Global LimitedSLGB$0.22-3.48%67.40K$9.99M$0.20 - $4.220.00%
4910Karyopharm Therapeutics Inc.KPTI$0.47-2.47%731.70K$10.68M$0.31 - $10.990.00%
4911Cycurion, Inc.CYCU$2.29-0.45%73.90K$7.40M$2.00 - $56.590.00%
4912Greenlane Holdings, Inc.GNLN$1.90+1.27%8.21K$1.32M$1.51 - $27.920.00%
4913OneConstruction Group LimitedONEG$0.79-8.57%45.26K$12.80M$0.64 - $14.950.00%
4914Cadrenal Therapeutics, Inc.CVKD$0.93+1.10%59.56K$3.31M$0.82 - $14.180.00%
4915Microvision Inc.MVIS$1.25-0.40%509.72K$29.86M$1.08 - $18.750.00%
4916Ernexa Therapeutics Inc.ERNA$1.98-6.60%7.11K$3.23M$1.84 - $71.500.00%
4917Evolution Metals & Technologies Corp.EMAT$1.42+0.71%429.09K$887.49M$1.28 - $24.090.00%
4918VivoSim Labs, Inc.VIVS$0.15-1.84%446.70K$2.52M$0.14 - $3.400.00%
4919CDT Environmental Technology Investment Holdings LimitedCDTG$1.03-5.22%100.81K$3.13M$0.73 - $16.930.00%
4920Bluejay Diagnostics, Inc.BJDX$0.59+2.96%28.83K$2.62M$0.56 - $9.520.00%
4921Click Holdings LimitedCLIK$0.67-14.05%291.47K$7.54M$0.60 - $11.800.00%
4922Cheer Holding, Inc.CHR$1.21-2.82%15.22K$2.22M$1.17 - $41.850.00%
4923Youxin Technology LtdYAAS$0.78-6.67%19.42K$5.31M$0.74 - $12.950.00%
4924Smart Powerr Corp.CREG$0.78-47.55%2.83M$0$0.00 - $26.600.00%
4925Neo-Concept International Group Holdings LimitedNCI$0.84+2.20%57.42K$2.24M$0.57 - $110.480.00%
4926SOBR Safe, Inc.SOBR$0.21-46.50%2.50M$0$0.03 - $3.730.00%
4927Rich Sparkle Holdings LimitedANPA$1.39-4.30%14.64K$25.22M$1.38 - $180.640.00%
4928Dogness (International) CorporationDOGZ$0.69+33.44%22.21K$5.87M$0.51 - $13.340.00%
4929TNL MediageneTNMG$3.07-1.10%5.85K$2.47M$2.45 - $92.880.00%
4930Fractyl Health, Inc.GUTS$0.89-18.36%1.04M$14.33M$0.87 - $29.340.00%
4931Wearable Devices Ltd.WLDS$1.38+3.84%8.46K$4.47M$1.15 - $28.620.00%
4932Baosheng Media Group Holdings LimitedBAOS$0.17+2.35%70.28K$5.81M$0.16 - $3.820.00%
4933Megan Holdings LimitedMGN$3.12+30.13%393.16K$2.47M$1.67 - $155.400.00%
4934E-Home Household Service Holdings LimitedEJH$1.38+4.17%2.88K$4.40M$1.01 - $26.500.00%
4935Olenox Industries Inc.OLOX$0.79-7.56%679.98K$1.31M$0.60 - $21.900.00%
4936Polaryx Therapeutics, Inc.PLYX$1.89-2.13%9.15K$92.22M$1.75 - $48.910.00%
4937Farmmi, Inc.FAMI$0.10-5.52%872.53K$553.67K$0.09 - $1.940.00%
4938Beyond Air, Inc.XAIR$2.23+4.44%8.01K$3.71M$2.05 - $53.200.00%
4939Sadot Group Inc.SDOT$7.24+1.53%18.61K$10.55M$2.63 - $145.800.00%
4940Eshallgo Inc.EHGO$2.19-1.63%48.45K$3.00M$2.13 - $49.050.00%
4941Actuate Therapeutics, Inc.ACTU$0.38-29.57%1.96M$9.08M$0.34 - $7.900.00%
4942Mobile-health Network SolutionsMNDR$0.90-2.07%61.58K$799.73K$0.71 - $32.520.00%
4943Reviva Pharmaceuticals Holdings, Inc.RVPH$0.000.00%0$0$0.26 - $15.400.00%
4944Tenon Medical, Inc.TNON$2.19+5.34%84.74K$5.89M$2.10 - $45.500.00%
4945Gossamer Bio, Inc.GOSS$9.74+6.01%106.72K$59.59M$8.29 - $309.600.00%
4946SurgePays, Inc.SURG$0.15+5.73%2.56M$7.83M$0.11 - $2.950.00%
4947BioAtla, Inc.BCAB$1.77-42.99%1.01M$0$0.96 - $71.500.00%
4948HCW Biologics Inc.HCWB$1.14+1.79%8.26K$2.55M$1.09 - $23.940.00%
49493 E Network Technology Group LtdMASK$0.69-5.45%275.68K$3.59M$0.64 - $16.630.00%
4950Mercer International Inc.MERC$0.13+6.93%689.61K$8.57M$0.12 - $2.850.62%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Nexentis Technologies Inc. (NXTS) currently leads with a 52-week gain of 92.09% as of 2026-10-27 19:33 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.